MST2_DROHY
ID MST2_DROHY Reviewed; 1391 AA.
AC Q08696;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 1.
DT 25-MAY-2022, entry version 51.
DE RecName: Full=Axoneme-associated protein mst101(2);
GN Name=mst101(2);
OS Drosophila hydei (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7224;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], CHARACTERIZATION, AND POLYMORPHISM.
RX PubMed=7957199; DOI=10.1111/j.1432-1033.1994.1089b.x;
RA Neesen J., Padmanabhan S., Buenemann H.;
RT "Tandemly arranged repeats of a novel highly charged 16-amino-acid motif
RT representing the major component of the sperm-tail-specific axoneme-
RT associated protein family Dhmst101 form extended alpha-helical rods within
RT the extremely elongated spermatozoa of Drosophila hydei.";
RL Eur. J. Biochem. 225:1089-1095(1994).
CC -!- FUNCTION: Possible structural role in the sperm tail.
CC -!- SUBCELLULAR LOCATION: Cytoplasm.
CC -!- TISSUE SPECIFICITY: Testis. Primary spermatocytes and early spermatids.
CC -!- DOMAIN: The predominant structure is alpha-helical.
CC -!- POLYMORPHISM: Length polymorphisms exist between different strains,
CC most likely caused by length variations within the tandem repeats.
CC {ECO:0000269|PubMed:7957199}.
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DR EMBL; X73481; CAA51876.1; -; Genomic_DNA.
DR PIR; S51364; S51364.
DR AlphaFoldDB; Q08696; -.
DR SMR; Q08696; -.
DR PRIDE; Q08696; -.
DR FlyBase; FBgn0020733; Dhyd\mst101(2).
DR GO; GO:0005737; C:cytoplasm; IDA:UniProtKB.
DR GO; GO:0007288; P:sperm axoneme assembly; IEP:UniProtKB.
PE 1: Evidence at protein level;
KW Cytoplasm; Repeat.
FT CHAIN 1..1391
FT /note="Axoneme-associated protein mst101(2)"
FT /id="PRO_0000096605"
FT REPEAT 332..347
FT /note="1"
FT REPEAT 348..363
FT /note="2"
FT REPEAT 364..379
FT /note="3"
FT REPEAT 380..395
FT /note="4"
FT REPEAT 396..411
FT /note="5"
FT REPEAT 412..427
FT /note="6"
FT REPEAT 428..443
FT /note="7"
FT REPEAT 444..459
FT /note="8"
FT REPEAT 460..475
FT /note="9"
FT REPEAT 476..491
FT /note="10"
FT REPEAT 492..507
FT /note="11"
FT REPEAT 508..523
FT /note="12"
FT REPEAT 524..539
FT /note="13"
FT REPEAT 540..555
FT /note="14"
FT REPEAT 556..571
FT /note="15"
FT REPEAT 572..587
FT /note="16"
FT REPEAT 588..603
FT /note="17"
FT REPEAT 604..619
FT /note="18"
FT REPEAT 620..635
FT /note="19"
FT REPEAT 636..651
FT /note="20"
FT REPEAT 652..667
FT /note="21"
FT REPEAT 668..683
FT /note="22"
FT REPEAT 684..699
FT /note="23"
FT REPEAT 700..715
FT /note="24"
FT REPEAT 716..731
FT /note="25"
FT REPEAT 732..747
FT /note="26"
FT REPEAT 748..763
FT /note="27"
FT REPEAT 764..779
FT /note="28"
FT REPEAT 780..795
FT /note="29"
FT REPEAT 796..811
FT /note="30"
FT REPEAT 812..827
FT /note="31"
FT REPEAT 828..843
FT /note="32"
FT REPEAT 844..859
FT /note="33"
FT REPEAT 860..875
FT /note="34"
FT REPEAT 876..891
FT /note="35"
FT REPEAT 892..907
FT /note="36"
FT REPEAT 908..923
FT /note="37"
FT REPEAT 924..939
FT /note="38"
FT REPEAT 940..955
FT /note="39"
FT REPEAT 956..971
FT /note="40"
FT REPEAT 972..987
FT /note="41"
FT REPEAT 988..1003
FT /note="42"
FT REPEAT 1004..1019
FT /note="43"
FT REPEAT 1020..1035
FT /note="44"
FT REPEAT 1036..1051
FT /note="45"
FT REPEAT 1052..1067
FT /note="46"
FT REPEAT 1068..1083
FT /note="47"
FT REPEAT 1084..1099
FT /note="48"
FT REPEAT 1100..1115
FT /note="49"
FT REPEAT 1116..1131
FT /note="50"
FT REPEAT 1132..1147
FT /note="51"
FT REPEAT 1148..1163
FT /note="52"
FT REPEAT 1164..1179
FT /note="53"
FT REPEAT 1180..1195
FT /note="54"
FT REPEAT 1196..1211
FT /note="55"
FT REPEAT 1212..1227
FT /note="56"
FT REPEAT 1228..1243
FT /note="57"
FT REPEAT 1244..1259
FT /note="58"
FT REPEAT 1260..1275
FT /note="59"
FT REGION 170..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 280..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 332..1275
FT /note="59 X 16 AA approximate tandem repeats of [KR]-K-X-C-
FT X-X-X-A-K-X-X-K-X-X-X-E"
FT REGION 370..429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 516..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 729..881
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 900..922
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 934..1013
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1076..1095
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1104..1212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1353..1391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..189
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..213
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 729..773
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 774..861
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 935..978
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 979..1013
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1366..1384
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1391 AA; 159002 MW; 1B2A368F30F48878 CRC64;
MSLCRCSSIC LRRPILRSFN FLNKYIDQSQ HSGGLSSFQR LSFSNTGKNE STDDSNQIRC
DADKTAADKK KQKQKEEEQA KIREYKRECL KVQKRVLAEE IRCSGEKDRI LIQGMMKCLT
DGMKKACTKI AKAKLIADKE LAVQCAALSK KDKVKALLKK CEREKSKEKE CNQNSPAEGD
KDRTKKGKTK GKSGGGNKKR STKENRAKKG KKLVKNRFTQ KLEHCIKSEW ADVCECRQNF
TEDERKRLAA SYKCMGTKIK SICRKRVIAE MCEAAGYVKS SEPKKKGKKK KNDEKKEKEL
EREILKEQAE EEAKIRGVVK EVKKKCKEKA LKKKCKDLGR KMKEEAEKKK CAALAKKQKE
EDEKKACKEL AKKKKEADEK KKCEEAANKE KKAAEKKKCE KAAKERKEAA EKKKCEEAAK
KEKEAAERKK CEELAKNIKK AAEKKKCKEA AKKEKEAAER KKCEELAKKI KKAAEKKKCE
ETAKKGKEVA ERKKCEELAK KIKKAEIKKK CKKLAKKEKE TAEKKKCEKA AKKRKEAAEK
KKCEKAAKKR KEAAEKKKCE KSAKKRKEAA EKKKCEKAAK ERKEAAEKKK CEEAAKKEKE
VAERKKCEEL AKKIKKAAEK KKCKEAAKKE KEAAEREKCG ELAKKIKKAA EKKKCKKLAK
KEKETAEKKK CEKAAKKRKE AAEKKKCAEA AKKEKEAAEK KKCEEAAKKE KEAAERKKCE
ELAKKIKKAA EKKKCKKLAK KKKAGEKNKL KKGNKKGKKA LKEKKKCREL AKKKAAEKKK
CKEAAKKEKE AAEKKKCEKT AKKRKEEAEK KKCEKTAKKR KEAAEKKKCE KAAKKRKEEA
EKKKCEKTAK KRKETAEKKK CEKAAKKRKQ AAEKKKCEKA AKKRKEAAEK KKCAEAAKKE
KELAEKKKCE EAAKKEKEVA ERKKCEELAK KIKKAAEKKK CKKLAKKEKK AGEKNKLKKK
AGKGKKKCKK LGKKSKRAAE KKKCAEAAKK EKEAATKKKC EERAKKQKEA AEKKQCEERA
KKLKEAAEQK QCEERAKKLK EAAEKKQCEE RAKKLKEAAE QKQCEERAKK LKEAAEKKQC
EERAKKEKEA AEKKQCEERA KKLKEAAEKK QCEERAKKEK EAAEKKRCEE AAKREKEAAE
KKKCAEAAKK EKEATEKQKC AEAAKKEKEA AEKKKCAEAA KREKEAAQKK KCADLAKKEQ
EPAEMKKCEE AAKKEKEAAE KQKCAKAAKK EKEAAEKKKC AEAAKKEQEA AEKKKCAEAA
KKEKEAEKKR KCEKAEKAAA LKRQCAKLVI RAKEAALRKK CAIIAKKAKM AAEKKECEKL
AKKAKEAIEW KKCAKLAKKK REAEKKKCAK LAKKEKEAAE KKKRCKDLAK NKKKGHKKKG
RNENRKKRTD C
