MST3_ORYSJ
ID MST3_ORYSJ Reviewed; 518 AA.
AC Q7EZD7; Q7XAK7; Q9FRT5;
DT 30-AUG-2017, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 150.
DE RecName: Full=Sugar transport protein MST3 {ECO:0000305};
DE AltName: Full=Monosaccharide transporter 3 {ECO:0000303|PubMed:11038054};
DE Short=OsMST3 {ECO:0000303|PubMed:11038054};
DE AltName: Full=Sugar:proton symporter MST3 {ECO:0000305};
GN Name=MST3 {ECO:0000303|PubMed:11038054};
GN OrderedLocusNames=Os07g0106200 {ECO:0000312|EMBL:BAF20618.1},
GN LOC_Os07g01560 {ECO:0000305};
GN ORFNames=B1317D11.119-1 {ECO:0000312|EMBL:BAD31944.1},
GN OsJ_22802 {ECO:0000312|EMBL:EAZ38424.1},
GN P0617C02.124-1 {ECO:0000312|EMBL:BAC10381.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, AND TISSUE SPECIFICITY.
RX PubMed=11038054; DOI=10.1093/pcp/pcd016;
RA Toyofuku K., Kasahara M., Yamaguchi J.;
RT "Characterization and expression of monosaccharide transporters (osMSTs) in
RT rice.";
RL Plant Cell Physiol. 41:940-947(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: Mediates active uptake of hexoses by sugar:proton symport.
CC Can transport glucose, xylose and 3-O-methylglucose. May be involved in
CC the accumulation of monosaccharides required for cell wall synthesis
CC during root development. {ECO:0000269|PubMed:11038054}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q7EZD7-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q7EZD7-2; Sequence=VSP_059026;
CC -!- TISSUE SPECIFICITY: Highly expressed in roots. Expressed in xylem and
CC sclerenchyma cells of roots. Expressed at low levels in leaves.
CC {ECO:0000269|PubMed:11038054}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB052885; BAB19864.1; -; mRNA.
DR EMBL; AP004673; BAC10381.1; -; Genomic_DNA.
DR EMBL; AP004673; BAC81184.1; -; Genomic_DNA.
DR EMBL; AP006186; BAD31944.1; -; Genomic_DNA.
DR EMBL; AP006186; BAD31945.1; -; Genomic_DNA.
DR EMBL; AP008213; BAF20618.1; -; Genomic_DNA.
DR EMBL; AP014963; BAS99714.1; -; Genomic_DNA.
DR EMBL; AP014963; BAS99715.1; -; Genomic_DNA.
DR EMBL; CM000144; EAZ38424.1; -; Genomic_DNA.
DR EMBL; AK099079; BAG93911.1; -; mRNA.
DR EMBL; AK103047; BAG95854.1; -; mRNA.
DR RefSeq; XP_015646448.1; XM_015790962.1. [Q7EZD7-1]
DR AlphaFoldDB; Q7EZD7; -.
DR SMR; Q7EZD7; -.
DR STRING; 4530.OS07T0106200-02; -.
DR PaxDb; Q7EZD7; -.
DR PRIDE; Q7EZD7; -.
DR EnsemblPlants; Os07t0106200-02; Os07t0106200-02; Os07g0106200. [Q7EZD7-1]
DR EnsemblPlants; Os07t0106200-03; Os07t0106200-03; Os07g0106200. [Q7EZD7-2]
DR GeneID; 4342198; -.
DR Gramene; Os07t0106200-02; Os07t0106200-02; Os07g0106200. [Q7EZD7-1]
DR Gramene; Os07t0106200-03; Os07t0106200-03; Os07g0106200. [Q7EZD7-2]
DR KEGG; osa:4342198; -.
DR eggNOG; KOG0254; Eukaryota.
DR InParanoid; Q7EZD7; -.
DR OMA; WFGRRIT; -.
DR OrthoDB; 430696at2759; -.
DR Proteomes; UP000000763; Chromosome 7.
DR Proteomes; UP000007752; Chromosome 7.
DR Proteomes; UP000059680; Chromosome 7.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015145; F:monosaccharide transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR CDD; cd17361; MFS_STP; 1.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR044778; MFS_STP/MST-like_plant.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR045262; STP/PLT_plant.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR PANTHER; PTHR23500; PTHR23500; 1.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; SSF103473; 1.
DR TIGRFAMs; TIGR00879; SP; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Membrane; Reference proteome; Sugar transport;
KW Symport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..518
FT /note="Sugar transport protein MST3"
FT /id="PRO_0000441037"
FT TOPO_DOM 1..18
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 19..39
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 40..80
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 102..117
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 118..138
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 139..140
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 141..161
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 162..167
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 168..188
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 189..202
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 203..223
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 224..290
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 291..311
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 312..322
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 323..343
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 344..351
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 352..372
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 373..387
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 388..408
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 409..427
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 428..448
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 449..452
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 453..473
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 474..518
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT VAR_SEQ 1..151
FT /note="MAGGAVVSTGAGKDYPGKLTLFVFFTCVVAATGGLIFGYDIGISGGVTSMDP
FT FLRKFFPEVYRKKQMADKNNQYCKYDNQLLQTFTSSLYLAALVSSFFAATVTRVLGRKW
FT SMFAGGLTFLIGAALNGAAENVAMLIVGRILLGVGVGFAN -> MMNGYDM (in
FT isoform 2)"
FT /id="VSP_059026"
SQ SEQUENCE 518 AA; 56765 MW; 1C13D682354C2F92 CRC64;
MAGGAVVSTG AGKDYPGKLT LFVFFTCVVA ATGGLIFGYD IGISGGVTSM DPFLRKFFPE
VYRKKQMADK NNQYCKYDNQ LLQTFTSSLY LAALVSSFFA ATVTRVLGRK WSMFAGGLTF
LIGAALNGAA ENVAMLIVGR ILLGVGVGFA NQSVPVYLSE MAPARLRGML NIGFQLMITI
GILAAELINY GTAKIKAGWG WRVSLALAAV PAAIITLGSL FLPDTPNSLI DRGHPEAAER
MLRRIRGSDV DVSEEYADLV AASEESKLVQ HPWRNILRRK YRAQLTMAIC IPFFQQLTGI
NVIMFYAPVL FDTLGFKSDA SLMSAVITGL VNVFATLVSI FTVDRLGRRK LFLQGGAQMV
VCQVVVGTLI AVKFGTSGIG DIPKGYAAVV VLFICMYVAG FAWSWGPLGW LVPSEIFPLE
IRPAGQSINV SVNMLFTFVI AQAFLTMLCH MKFGLFYFFA GWVVIMTVFI ALFLPETKNV
PIEEMVLVWK SHWFWRRFIG DHDVHVGANH VSNNKLQP
