ID   MSTO1_PONPY             Reviewed;         570 AA.
AC   Q5RF82; Q4GXY6; Q5R4A4;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Protein misato homolog 1;
GN   Name=MSTO1;
OS   Pongo pygmaeus (Bornean orangutan).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9600;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex, and Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 4-570.
RX   PubMed=16545939; DOI=10.1016/j.ygeno.2006.02.002;
RA   Kuryshev V.Y., Vorobyov E., Zink D., Schmitz J., Rozhdestvensky T.S.,
RA   Muenstermann E., Ernst U., Wellenreuther R., Moosmayer P., Bechtel S.,
RA   Schupp I., Horst J., Korn B., Poustka A., Wiemann S.;
RT   "An anthropoid-specific segmental duplication on human chromosome 1q22.";
RL   Genomics 88:143-151(2006).
CC   -!- FUNCTION: Involved in the regulation of mitochondrial distribution and
CC       morphology. Required for mitochondrial fusion and mitochondrial network
CC       formation. {ECO:0000250|UniProtKB:Q9BUK6}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane
CC       {ECO:0000250|UniProtKB:Q9BUK6}. Cytoplasm
CC       {ECO:0000250|UniProtKB:Q9BUK6}.
CC   -!- SIMILARITY: Belongs to the misato family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAJ15168.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; CR857279; CAH89575.1; -; mRNA.
DR   EMBL; CR861351; CAH93412.1; -; mRNA.
DR   EMBL; AM048759; CAJ15168.1; ALT_FRAME; mRNA.
DR   AlphaFoldDB; Q5RF82; -.
DR   GO; GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB.
DR   GO; GO:0048311; P:mitochondrion distribution; ISS:UniProtKB.
DR   GO; GO:0007005; P:mitochondrion organization; ISS:UniProtKB.
DR   Gene3D; 3.40.50.1440; -; 1.
DR   InterPro; IPR029209; DML1/Misato_tubulin.
DR   InterPro; IPR019605; Misato_II_tubulin-like.
DR   InterPro; IPR036525; Tubulin/FtsZ_GTPase_sf.
DR   Pfam; PF10644; Misat_Tub_SegII; 1.
DR   Pfam; PF14881; Tubulin_3; 1.
DR   SUPFAM; SSF52490; SSF52490; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Membrane; Mitochondrion; Mitochondrion outer membrane;
KW   Phosphoprotein.
FT   CHAIN           1..570
FT                   /note="Protein misato homolog 1"
FT                   /id="PRO_0000304629"
FT   MOD_RES         495
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BUK6"
FT   CONFLICT        73
FT                   /note="K -> E (in Ref. 1; CAH93412)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        210
FT                   /note="E -> G (in Ref. 1; CAH93412)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        334
FT                   /note="A -> V (in Ref. 2; CAJ15168)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        348
FT                   /note="S -> P (in Ref. 1; CAH93412)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        461
FT                   /note="V -> A (in Ref. 2; CAJ15168)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        495
FT                   /note="S -> F (in Ref. 1; CAH93412)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        548
FT                   /note="I -> V (in Ref. 1; CAH93412)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   570 AA;  61912 MW;  2C9FE197D3B09C19 CRC64;
     MAGGAREVLT LQLGHFAGFV GAHWWNQQDA ALGQATDSKE PLGELCPDVL YRTGRTLHGQ
     ETYTPRLILM DLKGSLSSLK EEGGLYRDKQ LDAAIAWQGK LTTHKEELYP KNPYLQDFLS
     AEGVLSSDGV WRVKSIPNGK GSPPLTTATT PKPLIPTEAS IRVWSDFLRV HLHPRSICMI
     QKYNHDGEAG RLEAFGQGES VLKEPKYQEE LEDRLHFYVE ECDYLQGFQI LCDLHDGFSG
     VGAKAAELLQ DEYSGRGIIT WGLLPGPYHR GEAQRNIYRL LNTAFGLVHL TAHSSLVCPL
     SLGGSLGLRP EPPVNFPYLH YDATLPFHCS AILATALDTV TVPYRLCSSP VSMVHLADML
     SFCGKKVVTA GAIIPFPLAP GQSLPDSLMQ FGGATPWTPL SACGEPSGTR CFAQSVVLRG
     IDRACHTSQL TPGTPPPSAL HACTTGEEVL AQYLQQQQPG VMSSSRLLLT PCRVAPPYPH
     LFSSCGPPGM VLDGSPKGAA VESIPVFGAL CSSSSLHQTL EALARDLTKL DLRRWASFMD
     AGVEHDDIAE LLQELQSLAQ CYQDGDSLVD