MT1A_ORYSI
ID MT1A_ORYSI Reviewed; 74 AA.
AC A2ZH20; O04739; O22489; Q40633; Q53MA9; Q53NN5; Q53WW8; Q6RUN8;
DT 24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 1.
DT 25-MAY-2022, entry version 50.
DE RecName: Full=Metallothionein-like protein 1A;
DE AltName: Full=Class I metallothionein-like protein 1A;
DE AltName: Full=OsMT-I-1a;
DE Short=OsMT1a;
GN Name=ERR26; Synonyms=MT-1, MT1A, RGMT-1; ORFNames=OsI_035863;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Milyang 23; TISSUE=Immature seed;
RA Kim Y.H., Lee M.C., Yun D.W., Eun M.Y.;
RT "Nucleotide sequences of cDNAs encoding three types of metallothionein(MT)-
RT like protein from Oryza sativa L.";
RL (er) Plant Gene Register PGR99-019(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. 93-11;
RA Yu T., Zhu Y.;
RT "Isolation of rice genes regulated by SA.";
RL Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Kumari S., Panjabi V., Singla-Pareek S.L., Sopory S.K., Pareek A.;
RT "A comparative transcriptome map of early and late salinity stress
RT responses in contrasting genotypes of Oryza sativa L.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RX PubMed=17002881; DOI=10.5483/bmbrep.2006.39.5.595;
RA Zhou G., Xu Y., Li J., Yang L., Liu J.-Y.;
RT "Molecular analyses of the metallothionein gene family in rice (Oryza
RT sativa L.).";
RL J. Biochem. Mol. Biol. 39:595-606(2006).
RN [6]
RP FUNCTION, AND INDUCTION.
RC STRAIN=cv. Pokkali;
RX PubMed=23385446; DOI=10.1007/s10930-013-9469-2;
RA Nezhad R.M., Shahpiri A., Mirlohi A.;
RT "Heterologous expression and metal-binding characterization of a type 1
RT metallothionein isoform (OsMTI-1b) from rice (Oryza sativa).";
RL Protein J. 32:131-137(2013).
CC -!- FUNCTION: Metallothioneins have a high content of cysteine residues
CC that bind various heavy metals (Probable). May be involved in ROS
CC homeostasis. May act as reactive oxygen species (ROS) scavenger in
CC response to salt stress (PubMed:23385446).
CC {ECO:0000269|PubMed:23385446, ECO:0000305}.
CC -!- INDUCTION: Down-regulated by salt stress.
CC {ECO:0000269|PubMed:23385446}.
CC -!- SIMILARITY: Belongs to the metallothionein superfamily. Type 15 family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF017366; AAB70546.1; -; mRNA.
DR EMBL; AY491534; AAR85965.1; -; mRNA.
DR EMBL; CM000136; EAY81904.1; -; Genomic_DNA.
DR EMBL; EF575936; ABR25524.1; -; mRNA.
DR AlphaFoldDB; A2ZH20; -.
DR STRING; 39946.A2ZH20; -.
DR EnsemblPlants; BGIOSGA035740-TA; BGIOSGA035740-PA; BGIOSGA035740.
DR Gramene; BGIOSGA035740-TA; BGIOSGA035740-PA; BGIOSGA035740.
DR HOGENOM; CLU_161105_0_1_1; -.
DR Proteomes; UP000007015; Chromosome 11.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR000347; Metalthion_15p.
DR PANTHER; PTHR33543; PTHR33543; 1.
DR Pfam; PF01439; Metallothio_2; 1.
PE 2: Evidence at transcript level;
KW Metal-binding; Metal-thiolate cluster; Reference proteome; Stress response.
FT CHAIN 1..74
FT /note="Metallothionein-like protein 1A"
FT /id="PRO_0000296353"
FT CONFLICT 35
FT /note="V -> A (in Ref. 1; AAB70546)"
FT /evidence="ECO:0000305"
FT CONFLICT 47
FT /note="Q -> H (in Ref. 1; AAB70546)"
FT /evidence="ECO:0000305"
FT CONFLICT 66
FT /note="S -> C (in Ref. 2; AAR85965)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 74 AA; 7482 MW; 56E3313EB5D1BE8F CRC64;
MSCSCGSSCS CGSNCSCGKK YPDLEEKSSS TKATVVLGVA PEKKAQQFEA AAESGETAHG
CSCGSSCRCN PCNC
