ID   MT1A_ORYSJ              Reviewed;          74 AA.
AC   P0C5B3; B9G8W2; O04739; O22489; Q40633; Q53MA9; Q53NN5; Q53WW8; Q6RUN8;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Metallothionein-like protein 1A;
DE   AltName: Full=Class I metallothionein-like protein 1A;
DE   AltName: Full=OsMT-I-1a;
DE            Short=OsMT1a;
GN   Name=MT1A; Synonyms=ERR26, MT-1, RGMT-1;
GN   OrderedLocusNames=Os11g0704500, LOC_Os11g47809;
GN   ORFNames=OsJ_34866 {ECO:0000312|EMBL:EEE52577.1};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], AND INDUCTION.
RC   STRAIN=cv. Tainung 67;
RX   PubMed=7632910; DOI=10.1007/bf00020388;
RA   Hsieh H.M., Liu W.K., Huang P.C.;
RT   "A novel stress-inducible metallothionein-like gene from rice.";
RL   Plant Mol. Biol. 28:381-389(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. Tainung 67;
RX   PubMed=9773271; DOI=10.3109/10425179809050020;
RA   Hsieh H.M., Huang P.C.;
RT   "Promoter structure and activity of type 1 rice metallothionein-like
RT   gene.";
RL   DNA Seq. 9:9-17(1998).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG   The rice chromosomes 11 and 12 sequencing consortia;
RT   "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT   genes and recent gene duplications.";
RL   BMC Biol. 3:20-20(2005).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [5]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [6]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [7]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [8]
RP   INDUCTION.
RX   PubMed=16912923; DOI=10.1007/s10529-006-9152-1;
RA   Jin S., Cheng Y., Guan Q., Liu D., Takano T., Liu S.;
RT   "A metallothionein-like protein of rice (rgMT) functions in E. coli and its
RT   gene expression is induced by abiotic stresses.";
RL   Biotechnol. Lett. 28:1749-1753(2006).
RN   [9]
RP   GENE FAMILY, AND TISSUE SPECIFICITY.
RX   PubMed=17002881; DOI=10.5483/bmbrep.2006.39.5.595;
RA   Zhou G., Xu Y., Li J., Yang L., Liu J.-Y.;
RT   "Molecular analyses of the metallothionein gene family in rice (Oryza
RT   sativa L.).";
RL   J. Biochem. Mol. Biol. 39:595-606(2006).
CC   -!- FUNCTION: Metallothioneins have a high content of cysteine residues
CC       that bind various heavy metals. May be involved in ROS homeostasis. May
CC       act as reactive oxygen species (ROS) scavenger in response to salt
CC       stress. {ECO:0000250|UniProtKB:A2ZH20}.
CC   -!- TISSUE SPECIFICITY: Expressed in leaves of mature plants.
CC       {ECO:0000269|PubMed:17002881}.
CC   -!- INDUCTION: Under different stress conditions, such as excess heavy
CC       metals, heat shock and salt stresses. {ECO:0000269|PubMed:16912923,
CC       ECO:0000269|PubMed:7632910}.
CC   -!- SIMILARITY: Belongs to the metallothionein superfamily. Type 15 family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAX95356.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; U18404; AAA80335.1; -; Genomic_DNA.
DR   EMBL; U43529; AAC49626.1; -; mRNA.
DR   EMBL; U46159; AAD10376.1; -; Genomic_DNA.
DR   EMBL; AC134045; AAX95356.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AC137064; AAX95268.1; -; Genomic_DNA.
DR   EMBL; AP008217; BAF28907.1; -; Genomic_DNA.
DR   EMBL; AP014967; BAT15399.1; -; Genomic_DNA.
DR   EMBL; CM000148; EEE52577.1; -; Genomic_DNA.
DR   PIR; S57768; S57768.
DR   RefSeq; XP_015617237.1; XM_015761751.1.
DR   AlphaFoldDB; P0C5B3; -.
DR   STRING; 4530.OS11T0704500-01; -.
DR   PaxDb; P0C5B3; -.
DR   PRIDE; P0C5B3; -.
DR   EnsemblPlants; Os11t0704500-01; Os11t0704500-01; Os11g0704500.
DR   GeneID; 4351213; -.
DR   Gramene; Os11t0704500-01; Os11t0704500-01; Os11g0704500.
DR   KEGG; osa:4351213; -.
DR   eggNOG; KOG4738; Eukaryota.
DR   HOGENOM; CLU_161105_0_1_1; -.
DR   InParanoid; P0C5B3; -.
DR   OMA; DSCKCNP; -.
DR   Proteomes; UP000000763; Chromosome 11.
DR   Proteomes; UP000007752; Chromosome 11.
DR   Proteomes; UP000059680; Chromosome 11.
DR   Genevisible; P0C5B3; OS.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR000347; Metalthion_15p.
DR   PANTHER; PTHR33543; PTHR33543; 1.
DR   Pfam; PF01439; Metallothio_2; 1.
PE   2: Evidence at transcript level;
KW   Metal-binding; Metal-thiolate cluster; Reference proteome; Stress response.
FT   CHAIN           1..74
FT                   /note="Metallothionein-like protein 1A"
FT                   /id="PRO_0000197379"
SQ   SEQUENCE   74 AA;  7482 MW;  56E3313EB5D1BE8F CRC64;
     MSCSCGSSCS CGSNCSCGKK YPDLEEKSSS TKATVVLGVA PEKKAQQFEA AAESGETAHG
     CSCGSSCRCN PCNC