ID   MT1B_ARATH              Reviewed;          45 AA.
AC   Q38803; A8MQW4;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Putative metallothionein-like protein 1B;
DE            Short=MT-1B;
GN   Name=MT1B; OrderedLocusNames=At5g56795; ORFNames=MIK19;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=7565594; DOI=10.1007/bf02191599;
RA   Zhou J., Goldsbrough P.B.;
RT   "Structure, organization and expression of the metallothionein gene family
RT   in Arabidopsis.";
RL   Mol. Gen. Genet. 248:318-328(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9734815; DOI=10.1093/dnares/5.3.203;
RA   Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence
RT   features of the regions of 1,367,185 bp covered by 19 physically assigned
RT   P1 and TAC clones.";
RL   DNA Res. 5:203-216(1998).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [4]
RP   FUNCTION.
RX   PubMed=16240177; DOI=10.1007/s11103-005-8268-3;
RA   Zimeri A.M., Dhankher O.P., McCaig B., Meagher R.B.;
RT   "The plant MT1 metallothioneins are stabilized by binding cadmiums and are
RT   required for cadmium tolerance and accumulation.";
RL   Plant Mol. Biol. 58:839-855(2005).
CC   -!- FUNCTION: Metallothioneins have a high content of cysteine residues
CC       that bind various heavy metals (Probable). Confers tolerance to cadmium
CC       (Cd) and plays a role in Cd and zinc (Zn) homeostasis
CC       (PubMed:16240177). {ECO:0000269|PubMed:16240177, ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the metallothionein superfamily. Type 15 family.
CC       {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AB013392; Type=Frameshift; Evidence={ECO:0000305};
CC       Sequence=AED96808.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=AED96808.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; U11254; AAA82210.1; -; Genomic_DNA.
DR   EMBL; AB013392; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002688; AED96808.1; ALT_SEQ; Genomic_DNA.
DR   PIR; S57859; S57859.
DR   RefSeq; NP_001032085.2; NM_001037008.3.
DR   AlphaFoldDB; Q38803; -.
DR   PeptideAtlas; Q38803; -.
DR   PRIDE; Q38803; -.
DR   GeneID; 3771524; -.
DR   KEGG; ath:AT5G56795; -.
DR   Araport; AT5G56795; -.
DR   TAIR; locus:1009023469; AT5G56795.
DR   Proteomes; UP000006548; Chromosome 5.
DR   GO; GO:0046872; F:metal ion binding; ISS:TAIR.
DR   GO; GO:0010038; P:response to metal ion; ISS:TAIR.
PE   5: Uncertain;
KW   Metal-binding; Metal-thiolate cluster; Reference proteome.
FT   CHAIN           1..45
FT                   /note="Putative metallothionein-like protein 1B"
FT                   /id="PRO_0000197420"
SQ   SEQUENCE   45 AA;  4811 MW;  F7E196F2E588066D CRC64;
     MGLILTRMIL NCGCGSSCKC GDSCSCEKNY NKECDNCSCG SNCNF