ID   MT1B_ORYSJ              Reviewed;          72 AA.
AC   Q10N03; A3AGU4;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Metallothionein-like protein 1B;
DE   AltName: Full=Class I metallothionein-like protein 1B;
DE   AltName: Full=OsMT-I-1b;
GN   Name=MT1B; OrderedLocusNames=Os03g0288000, LOC_Os03g17870;
GN   ORFNames=OsJ_10428 {ECO:0000312|EMBL:EAZ26533.1};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16109971; DOI=10.1101/gr.3869505;
RG   The rice chromosome 3 sequencing consortium;
RA   Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA   Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA   Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA   Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA   Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA   Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA   Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA   Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA   Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA   Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA   O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA   Jin W., Lee H.R., Jiang J., Jackson S.;
RT   "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT   and diverged grass species.";
RL   Genome Res. 15:1284-1291(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [6]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [7]
RP   GENE FAMILY, AND TISSUE SPECIFICITY.
RX   PubMed=17002881; DOI=10.5483/bmbrep.2006.39.5.595;
RA   Zhou G., Xu Y., Li J., Yang L., Liu J.-Y.;
RT   "Molecular analyses of the metallothionein gene family in rice (Oryza
RT   sativa L.).";
RL   J. Biochem. Mol. Biol. 39:595-606(2006).
RN   [8]
RP   FUNCTION.
RX   PubMed=23385446; DOI=10.1007/s10930-013-9469-2;
RA   Nezhad R.M., Shahpiri A., Mirlohi A.;
RT   "Heterologous expression and metal-binding characterization of a type 1
RT   metallothionein isoform (OsMTI-1b) from rice (Oryza sativa).";
RL   Protein J. 32:131-137(2013).
CC   -!- FUNCTION: Metallothioneins have a high content of cysteine residues
CC       that bind various heavy metals (Probable). Functions as metal chelator
CC       of nickel (Ni), cadmium (Cd), zinc (Zn) and copper (Cu). Possesses
CC       higher affinity for Ni and Cd ions compared to Zn and Cu ions
CC       (PubMed:23385446). {ECO:0000269|PubMed:23385446, ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed in leaves of mature plants.
CC       {ECO:0000269|PubMed:17002881}.
CC   -!- SIMILARITY: Belongs to the metallothionein superfamily. Type 15 family.
CC       {ECO:0000305}.
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DR   EMBL; DP000009; ABF95371.1; -; Genomic_DNA.
DR   EMBL; AP008209; BAF11696.1; -; Genomic_DNA.
DR   EMBL; AP014959; BAS83644.1; -; Genomic_DNA.
DR   EMBL; CM000140; EAZ26533.1; -; Genomic_DNA.
DR   EMBL; AK059587; BAG87041.1; -; mRNA.
DR   EMBL; AK103162; BAG95928.1; -; mRNA.
DR   RefSeq; XP_015628821.1; XM_015773335.1.
DR   AlphaFoldDB; Q10N03; -.
DR   STRING; 4530.OS03T0288000-01; -.
DR   PaxDb; Q10N03; -.
DR   PRIDE; Q10N03; -.
DR   EnsemblPlants; Os03t0288000-01; Os03t0288000-01; Os03g0288000.
DR   EnsemblPlants; Os03t0288000-02; Os03t0288000-02; Os03g0288000.
DR   GeneID; 4332487; -.
DR   Gramene; Os03t0288000-01; Os03t0288000-01; Os03g0288000.
DR   Gramene; Os03t0288000-02; Os03t0288000-02; Os03g0288000.
DR   KEGG; osa:4332487; -.
DR   eggNOG; KOG4738; Eukaryota.
DR   HOGENOM; CLU_161105_1_0_1; -.
DR   InParanoid; Q10N03; -.
DR   OrthoDB; 1627904at2759; -.
DR   Proteomes; UP000000763; Chromosome 3.
DR   Proteomes; UP000007752; Chromosome 3.
DR   Proteomes; UP000059680; Chromosome 3.
DR   Genevisible; Q10N03; OS.
DR   GO; GO:0046870; F:cadmium ion binding; IDA:UniProtKB.
DR   GO; GO:0005507; F:copper ion binding; IDA:UniProtKB.
DR   GO; GO:0016151; F:nickel cation binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   InterPro; IPR000347; Metalthion_15p.
DR   PANTHER; PTHR33543; PTHR33543; 1.
DR   Pfam; PF01439; Metallothio_2; 1.
PE   2: Evidence at transcript level;
KW   Metal-binding; Metal-thiolate cluster; Reference proteome.
FT   CHAIN           1..72
FT                   /note="Metallothionein-like protein 1B"
FT                   /id="PRO_0000263055"
SQ   SEQUENCE   72 AA;  7134 MW;  4D59D3BA198F3466 CRC64;
     MSCSCGSSCG CGSNCTCGKM YPDLEEKSSS AQATVVLGVA PEKAHFEAAA ESGETAHGCG
     CGSSCKCNPC NC