MT1_DROAN
ID MT1_DROAN Reviewed; 40 AA.
AC P61873; P22254;
DT 07-JUN-2004, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2004, sequence version 1.
DT 25-MAY-2022, entry version 47.
DE RecName: Full=Metallothionein-1;
DE Short=MT-1;
GN Name=MtnA;
OS Drosophila ananassae (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7217;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8001781; DOI=10.1093/genetics/138.1.135;
RA Stephan W., Rodriguez V.S., Zhou B., Parsch J.;
RT "Molecular evolution of the metallothionein gene Mtn in the melanogaster
RT species group: results from Drosophila ananassae.";
RL Genetics 138:135-143(1994).
CC -!- FUNCTION: This protein binds cations of several transition elements. It
CC is thought to be involved in detoxification processes.
CC -!- DEVELOPMENTAL STAGE: Late embryogenesis, larva and adult.
CC -!- INDUCTION: Strongly induced by cadmium, copper and mercury.
CC -!- DOMAIN: All cysteine residues are arranged in C-X-C groups. These are
CC thought to be the metal-binding sites in other metallothioneins.
CC -!- SIMILARITY: Belongs to the metallothionein superfamily. Type 5 family.
CC {ECO:0000305}.
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DR EMBL; S75822; AAB32801.2; -; Genomic_DNA.
DR AlphaFoldDB; P61873; -.
DR STRING; 7217.FBpp0120344; -.
DR eggNOG; KOG4738; Eukaryota.
DR ChiTaRS; MtnA; fly.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR000966; Metalthion_5.
DR Pfam; PF02067; Metallothio_5; 1.
DR PRINTS; PR00872; MTDIPTERA.
PE 2: Evidence at transcript level;
KW Cadmium; Copper; Metal-binding; Zinc.
FT CHAIN 1..40
FT /note="Metallothionein-1"
FT /id="PRO_0000197352"
SQ SEQUENCE 40 AA; 3852 MW; 9182A53CCCAE634A CRC64;
MPCPCGSGCK CASQATKGSC NCGSDCKCGG DKKSACGCSK