MT23A_MYTED
ID MT23A_MYTED Reviewed; 72 AA.
AC P69153; P80253; Q9GU31;
DT 15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 32.
DE RecName: Full=Metallothionein 20-III isoform A;
DE Short=MT-20-IIIA;
OS Mytilus edulis (Blue mussel).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Mytilida; Mytiloidea; Mytilidae; Mytilinae;
OC Mytilus.
OX NCBI_TaxID=6550;
RN [1]
RP PROTEIN SEQUENCE OF 2-72.
RX PubMed=8243463; DOI=10.1111/j.1432-1033.1993.tb18364.x;
RA Mackay E.A., Overnell J., Dunbar B., Davidson I., Hunziker P.E.,
RA Kaegi J.H.R., Fothergill J.E.;
RT "Complete amino acid sequences of five dimeric and four monomeric forms of
RT metallothionein from the edible mussel Mytilus edulis.";
RL Eur. J. Biochem. 218:183-194(1993).
CC -!- FUNCTION: The metallothioneins are involved in the cellular
CC sequestration of toxic metal ions.
CC -!- SUBUNIT: Homodimer.
CC -!- INDUCTION: By cadmium.
CC -!- SIMILARITY: Belongs to the metallothionein superfamily. Type 2 family.
CC {ECO:0000305}.
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DR PIR; S39422; S39422.
DR AlphaFoldDB; P69153; -.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR001008; Metalthion_mollusc.
DR PRINTS; PR00875; MTMOLLUSC.
PE 1: Evidence at protein level;
KW Cadmium; Direct protein sequencing; Metal-binding; Metal-thiolate cluster.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|PubMed:8243463"
FT CHAIN 2..72
FT /note="Metallothionein 20-III isoform A"
FT /id="PRO_0000197331"
FT BINDING 15
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 19
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 19
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 24
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 26
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="3"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 30
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="3"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 32
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 32
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="3"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 36
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 38
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 41
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 41
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="3"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 45
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="4"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 47
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="5"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 51
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="5"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 53
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="5"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 53
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="6"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 57
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="4"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 57
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="5"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 63
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="4"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 65
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="6"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 69
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="6"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 71
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="4"
FT /evidence="ECO:0000250|UniProtKB:P33187"
FT BINDING 71
FT /ligand="Cd(2+)"
FT /ligand_id="ChEBI:CHEBI:48775"
FT /ligand_label="6"
FT /evidence="ECO:0000250|UniProtKB:P33187"
SQ SEQUENCE 72 AA; 7030 MW; 12868683A0857631 CRC64;
MPGPCNCIET NVCICGTGCS GKCCQCGDAC KCASGCGCSG CKVVCRCSGT CACGCDCTGP
INCKCESGCS CK
