ID   MT25B_BOVIN             Reviewed;         475 AA.
AC   Q5E9V4;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=Methyltransferase-like protein 25B;
DE   AltName: Full=Protein RRNAD1 {ECO:0000250|UniProtKB:Q96FB5};
GN   Name=METTL25B {ECO:0000250|UniProtKB:Q96FB5}; Synonyms=RRNAD1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the METTL25 family. {ECO:0000305}.
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DR   EMBL; BT020816; AAX08833.1; -; mRNA.
DR   RefSeq; NP_001015641.1; NM_001015641.1.
DR   AlphaFoldDB; Q5E9V4; -.
DR   STRING; 9913.ENSBTAP00000001990; -.
DR   PaxDb; Q5E9V4; -.
DR   PRIDE; Q5E9V4; -.
DR   GeneID; 532204; -.
DR   KEGG; bta:532204; -.
DR   CTD; 51093; -.
DR   eggNOG; KOG2651; Eukaryota.
DR   InParanoid; Q5E9V4; -.
DR   OrthoDB; 1014832at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000179; F:rRNA (adenine-N6,N6-)-dimethyltransferase activity; IEA:InterPro.
DR   InterPro; IPR025714; Methyltranfer_dom.
DR   InterPro; IPR020596; rRNA_Ade_Mease_Trfase_CS.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF13679; Methyltransf_32; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..475
FT                   /note="Methyltransferase-like protein 25B"
FT                   /id="PRO_0000289051"
FT   TRANSMEM        406..426
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   COILED          186..210
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   475 AA;  53207 MW;  C0BF00B223B6863D CRC64;
     MPGVSARRLS HEERRQLAVN LTRVVTLYRS ILDAYIIEFF TDNLWGTLPC SWQEALDGLN
     PPQLATLLLG MPREGEVARY RSVWPLTLLA LKSTAYALAF TRTPGFQTPS EFLENPSQSS
     RLTAPFRKHV RPKKQHEIRR LGELVKKLSD LTGCTQVVDV GSGQGHLSRF MSLGLGLMVK
     SIEGDQRLVE RAQRLDQELL QTLEKEEKRN PKVVQTGPRH PPHHVVRWVD PTTLCEELLL
     PLETSPQSRA RLLLTGLHAC GDLSVALLKH FCCCPEVVAL ASVGCCYMKL SDPGGYPLSQ
     WVAGLPGYEL PYRLREGACH ALEEYAERLQ KAGPSLRTHC YRAALETVIR CAQPELRRPG
     VQGIPRVHEL KIEEYVQRGL QRVGLDPHLP LNVAALRAHQ AQENRVVAFF SLALLLAPLV
     ETLILLDRLL YLQEQGFHAE LLPIFSPELS PRNLVLVATK GPLGEAFSLL ETEDN