ID   MT25B_RAT               Reviewed;         475 AA.
AC   Q6AYG0;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Methyltransferase-like protein 25B;
DE   AltName: Full=Protein RRNAD1 {ECO:0000250|UniProtKB:Q96FB5};
GN   Name=Mettl25b {ECO:0000312|RGD:1311265}; Synonyms=Rrnad1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the METTL25 family. {ECO:0000305}.
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DR   EMBL; BC079059; AAH79059.1; -; mRNA.
DR   RefSeq; NP_001014195.1; NM_001014173.1.
DR   AlphaFoldDB; Q6AYG0; -.
DR   STRING; 10116.ENSRNOP00000015793; -.
DR   PaxDb; Q6AYG0; -.
DR   PRIDE; Q6AYG0; -.
DR   Ensembl; ENSRNOT00000015793; ENSRNOP00000015793; ENSRNOG00000011645.
DR   GeneID; 361976; -.
DR   KEGG; rno:361976; -.
DR   UCSC; RGD:1311265; rat.
DR   CTD; 51093; -.
DR   RGD; 1311265; Mettl25b.
DR   eggNOG; KOG2651; Eukaryota.
DR   GeneTree; ENSGT00530000063745; -.
DR   HOGENOM; CLU_016581_3_0_1; -.
DR   InParanoid; Q6AYG0; -.
DR   OMA; IVGLHPC; -.
DR   OrthoDB; 1014832at2759; -.
DR   PhylomeDB; Q6AYG0; -.
DR   TreeFam; TF312998; -.
DR   PRO; PR:Q6AYG0; -.
DR   Proteomes; UP000002494; Chromosome 2.
DR   Bgee; ENSRNOG00000011645; Expressed in thymus and 19 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR025714; Methyltranfer_dom.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF13679; Methyltransf_32; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..475
FT                   /note="Methyltransferase-like protein 25B"
FT                   /id="PRO_0000289054"
FT   TRANSMEM        406..426
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   COILED          185..210
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   475 AA;  53023 MW;  B70FDA8816AACAFC CRC64;
     MPGVSAHGLS CEERRQLAVD LTRVLALYRS ILDAYIIEFF TDSLWGTLPH AWQEVLDGLN
     PPELATLLLG MPREGEEIRY RSVWPLTLLA LKSTACALAF TRTPGFHTPS EFLENPSQSS
     RLTAPFRKHV KPKKQHEIRR LGELVKKLSD LTGCTQVVDV GSGQGHLSRF MSLGLGLMVK
     SLEGNKRLVA RAQRLDQELL QALDKMEKRH PKMVQRSPRH RPHHVVQWVS PTTLCEELLL
     PLEMPGQSST RLLLTGLHAC GDLSVALLRH FCCCPEVVAL ASVGCCYMKL SDPGSYPLSQ
     WVAGLPGHEL PYRLREGACH ALEDYAERLQ KAGPGLQTHC FRAALEAVIR QVCPELRRPG
     VQGIPRVHEL KIEEYVQQGL QRVGLDPQLP LDQAALQAHQ AQENRVVAFF SLALLLAPLV
     ETLILLDRML YLQEQGFYAE LLPIFSPELS PRNLVLVATK TPLGQAFSIL ETEDS