MT2A_ORYSJ
ID MT2A_ORYSJ Reviewed; 82 AA.
AC P94029; A2ZPA2; Q0JQN6; Q7F7X9;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1997, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Metallothionein-like protein 2A;
DE AltName: Full=Class I metallothionein-like protein 2A;
DE AltName: Full=OsMT-I-2a;
DE Short=OsMT2a;
DE AltName: Full=OsMT2-1;
GN Name=MT2A; Synonyms=MT-2; OrderedLocusNames=Os01g0149800, LOC_Os01g05650;
GN ORFNames=OsJ_00383 {ECO:0000312|EMBL:EAZ10549.1}, P0434B04.33;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], AND INDUCTION.
RC STRAIN=cv. Tainung 67; TISSUE=Root;
RX PubMed=8980501; DOI=10.1007/bf00019104;
RA Hsieh H.M., Liu W.K., Chang A., Huang P.C.;
RT "RNA expression patterns of a type 2 metallothionein-like gene from rice.";
RL Plant Mol. Biol. 32:525-529(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RG The rice full-length cDNA consortium;
RT "Oryza sativa full length cDNA.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [8]
RP GENE FAMILY, AND TISSUE SPECIFICITY.
RX PubMed=17002881; DOI=10.5483/bmbrep.2006.39.5.595;
RA Zhou G., Xu Y., Li J., Yang L., Liu J.-Y.;
RT "Molecular analyses of the metallothionein gene family in rice (Oryza
RT sativa L.).";
RL J. Biochem. Mol. Biol. 39:595-606(2006).
CC -!- FUNCTION: Metallothioneins have a high content of cysteine residues
CC that bind various heavy metals. {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in stems, leaves, rachis, inflorescences
CC and seeds. {ECO:0000269|PubMed:17002881}.
CC -!- INDUCTION: By sucrose starvation, heat shock and abscisic acid (ABA).
CC Not induced by heavy metals. {ECO:0000269|PubMed:8980501}.
CC -!- SIMILARITY: Belongs to the metallothionein superfamily. Type 15 family.
CC {ECO:0000305}.
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DR EMBL; U43530; AAC49627.1; -; mRNA.
DR EMBL; D89931; BAA14038.1; -; Genomic_DNA.
DR EMBL; AP002540; BAB44010.1; -; Genomic_DNA.
DR EMBL; AP008207; BAF03942.1; -; Genomic_DNA.
DR EMBL; AP014957; BAS70408.1; -; Genomic_DNA.
DR EMBL; CM000138; EAZ10549.1; -; Genomic_DNA.
DR EMBL; AK243576; BAH01656.1; -; mRNA.
DR PIR; T03727; T03727.
DR RefSeq; XP_015645115.1; XM_015789629.1.
DR AlphaFoldDB; P94029; -.
DR STRING; 4530.OS01T0149800-01; -.
DR PaxDb; P94029; -.
DR PRIDE; P94029; -.
DR EnsemblPlants; Os01t0149800-01; Os01t0149800-01; Os01g0149800.
DR GeneID; 4325218; -.
DR Gramene; Os01t0149800-01; Os01t0149800-01; Os01g0149800.
DR KEGG; osa:4325218; -.
DR eggNOG; KOG4738; Eukaryota.
DR HOGENOM; CLU_161105_1_0_1; -.
DR InParanoid; P94029; -.
DR OMA; NPCKCGK; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000007752; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR Genevisible; P94029; OS.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR000347; Metalthion_15p.
DR PANTHER; PTHR33543; PTHR33543; 1.
DR Pfam; PF01439; Metallothio_2; 1.
PE 2: Evidence at transcript level;
KW Metal-binding; Metal-thiolate cluster; Reference proteome; Stress response.
FT CHAIN 1..82
FT /note="Metallothionein-like protein 2A"
FT /id="PRO_0000197407"
SQ SEQUENCE 82 AA; 7852 MW; 8DCD62B8B6E503C4 CRC64;
MSCCGGNCGC GSGCQCGSGC GGCKMYPEMA EEVTTTQTVI MGVAPSKGHA EGLEAGAAAG
AGAENGCKCG DNCTCNPCNC GK
