MT2C_ORYSI
ID MT2C_ORYSI Reviewed; 84 AA.
AC A2XZL0; A5JVN2; P93433; Q0DLB2; Q65XV5;
DT 24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 1.
DT 25-MAY-2022, entry version 55.
DE RecName: Full=Metallothionein-like protein 2C;
DE AltName: Full=Class I metallothionein-like protein 2C;
DE AltName: Full=OsMT-I-2c;
DE AltName: Full=OsMT2b;
GN Name=MT2C; Synonyms=MT2BL; ORFNames=OsI_017503;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Milyang 23;
RA Lee M.C., Park J.Y., Lee J.S., Eun M.Y.;
RT "Molecular cloning and characterization of a metallothionein-like protein
RT gene in rice.";
RL Submitted (DEC-1996) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Jiayu 948;
RX PubMed=18258694; DOI=10.1104/pp.107.110304;
RA Yuan J., Chen D., Ren Y., Zhang X., Zhao J.;
RT "Characteristic and expression analysis of a metallothionein gene, OsMT2b,
RT down-regulated by cytokinin suggests functions in root development and seed
RT embryo germination of rice.";
RL Plant Physiol. 146:1637-1650(2008).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [4]
RP GENE FAMILY.
RX PubMed=17002881; DOI=10.5483/bmbrep.2006.39.5.595;
RA Zhou G., Xu Y., Li J., Yang L., Liu J.-Y.;
RT "Molecular analyses of the metallothionein gene family in rice (Oryza
RT sativa L.).";
RL J. Biochem. Mol. Biol. 39:595-606(2006).
CC -!- FUNCTION: Metallothioneins have a high content of cysteine residues
CC that bind various heavy metals. Acts as reactive oxygen species (ROS)
CC scavenger in the cytosol. Possesses superoxide anion and hydroxyl
CC radical scavenging activities in vitro. Plays a role during root
CC development, lateral root initiation and seed embryo germination,
CC possibly by regulating levels of cytokinin.
CC {ECO:0000250|UniProtKB:A3AZ88}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000250|UniProtKB:A3AZ88}.
CC -!- SIMILARITY: Belongs to the metallothionein superfamily. Type 15 family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U77294; AAB18814.1; -; mRNA.
DR EMBL; Y08529; CAA69845.1; -; mRNA.
DR EMBL; EF584509; ABQ57494.1; -; mRNA.
DR EMBL; CM000130; EAY96270.1; -; Genomic_DNA.
DR PIR; T03787; T03787.
DR AlphaFoldDB; A2XZL0; -.
DR STRING; 39946.A2XZL0; -.
DR EnsemblPlants; BGIOSGA019039-TA; BGIOSGA019039-PA; BGIOSGA019039.
DR Gramene; BGIOSGA019039-TA; BGIOSGA019039-PA; BGIOSGA019039.
DR HOGENOM; CLU_161105_1_0_1; -.
DR OMA; TCTAVCA; -.
DR Proteomes; UP000007015; Chromosome 5.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0072593; P:reactive oxygen species metabolic process; IEA:EnsemblPlants.
DR InterPro; IPR000347; Metalthion_15p.
DR PANTHER; PTHR33543; PTHR33543; 1.
DR Pfam; PF01439; Metallothio_2; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Metal-binding; Metal-thiolate cluster; Reference proteome;
KW Stress response.
FT CHAIN 1..84
FT /note="Metallothionein-like protein 2C"
FT /id="PRO_0000296354"
FT CONFLICT 21
FT /note="G -> S (in Ref. 2; ABQ57494)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 84 AA; 7969 MW; 5BF71575A9142311 CRC64;
MSCCGGNCGC GSGCQCGGGC GGCKMFPDVE ATATTKTFVL AAPSNKASSG GMEMAVESGE
NGGCGCNTCK CGTSCSGCSC CSCN
