MTB12_MYCLE
ID MTB12_MYCLE Reviewed; 167 AA.
AC Q49771;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 27-APR-2001, sequence version 2.
DT 25-MAY-2022, entry version 95.
DE RecName: Full=Low molecular weight antigen MTB12 homolog;
DE Flags: Precursor;
GN Name=mtb12; OrderedLocusNames=ML0620; ORFNames=B1937_F3_91;
OS Mycobacterium leprae (strain TN).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=272631;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Smith D.R., Robison K.;
RL Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TN;
RX PubMed=11234002; DOI=10.1038/35059006;
RA Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA Barrell B.G.;
RT "Massive gene decay in the leprosy bacillus.";
RL Nature 409:1007-1011(2001).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MTB12 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA17178.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; U00016; AAA17178.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL583919; CAC30128.1; -; Genomic_DNA.
DR PIR; D86986; D86986.
DR PIR; S72610; S72610.
DR RefSeq; NP_301516.1; NC_002677.1.
DR RefSeq; WP_010907840.1; NC_002677.1.
DR AlphaFoldDB; Q49771; -.
DR EnsemblBacteria; CAC30128; CAC30128; CAC30128.
DR KEGG; mle:ML0620; -.
DR PATRIC; fig|272631.5.peg.1098; -.
DR Leproma; ML0620; -.
DR eggNOG; ENOG5030PBH; Bacteria.
DR HOGENOM; CLU_129262_0_0_11; -.
DR OMA; FVNQGSW; -.
DR Proteomes; UP000000806; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE 3: Inferred from homology;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..167
FT /note="Low molecular weight antigen MTB12 homolog"
FT /id="PRO_0000021776"
SQ SEQUENCE 167 AA; 17131 MW; 3DC3BC2B542CA519 CRC64;
MTMKSIATYA ALAIIGAAVD GLTSMAIPTG PAASHIQPVA FGVPLPQDPA PAADVPTAAE
LTSLLNKIVD PDVSFMHKSQ LVEGGIGSAE AHIGDRELKN AAQKGELPLL FSVTNIRPGT
SGSATADVSV SGPKLNPPVT QNITFINKGS WVLSRHSAME LLQAAGR