ID   MTB12_MYCTO             Reviewed;         168 AA.
AC   P9WIN6; L0T9F9; O05822; P0A5P8;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 26.
DE   RecName: Full=Low molecular weight antigen MTB12;
DE   AltName: Full=CFP-2;
DE   AltName: Full=Low molecular weight protein antigen 2;
DE   Flags: Precursor;
GN   Name=mtb12; Synonyms=cfp2; OrderedLocusNames=MT2445;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: May play a role in the development of protective immune
CC       responses. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MTB12 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE000516; AAK46739.1; -; Genomic_DNA.
DR   PIR; G70587; G70587.
DR   RefSeq; WP_003917622.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WIN6; -.
DR   EnsemblBacteria; AAK46739; AAK46739; MT2445.
DR   KEGG; mtc:MT2445; -.
DR   PATRIC; fig|83331.31.peg.2635; -.
DR   HOGENOM; CLU_129262_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Secreted; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   PROPEP          23..48
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000427973"
FT   CHAIN           49..168
FT                   /note="Low molecular weight antigen MTB12"
FT                   /id="PRO_0000427974"
SQ   SEQUENCE   168 AA;  16663 MW;  A80990446B009BFD CRC64;
     MKMVKSIAAG LTAAAAIGAA AAGVTSIMAG GPVVYQMQPV VFGAPLPLDP ASAPDVPTAA
     QLTSLLNSLA DPNVSFANKG SLVEGGIGGT EARIADHKLK KAAEHGDLPL SFSVTNIQPA
     AAGSATADVS VSGPKLSSPV TRNVTFVNQG GWMLSRASAM ELLQAAGN