ID   MTB_STRPU               Reviewed;          65 AA.
AC   Q27287;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Metallothionein-B;
DE            Short=MTB;
GN   Name=MTB1; Synonyms=MTB;
OS   Strongylocentrotus purpuratus (Purple sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae;
OC   Strongylocentrotus.
OX   NCBI_TaxID=7668;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=3561398; DOI=10.1128/mcb.7.1.48-58.1987;
RA   Wilkinson D.G., Nemer M.;
RT   "Metallothionein genes MTa and MTb expressed under distinct quantitative
RT   and tissue-specific regulation in sea urchin embryos.";
RL   Mol. Cell. Biol. 7:48-58(1987).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2007604; DOI=10.1016/s0021-9258(18)38157-2;
RA   Nemer M., Thornton R.D., Stuebing E.W., Harlow P.;
RT   "Structure, spatial, and temporal expression of two sea urchin
RT   metallothionein genes, SpMTB1 and SpMTA.";
RL   J. Biol. Chem. 266:6586-6593(1991).
CC   -!- FUNCTION: Metallothioneins have a high content of cysteine residues
CC       that bind various heavy metals.
CC   -!- INDUCTION: By heavy metals.
CC   -!- SIMILARITY: Belongs to the metallothionein superfamily. Type 4 family.
CC       {ECO:0000305}.
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DR   EMBL; M15989; AAA30063.1; -; mRNA.
DR   EMBL; M59822; AAA30062.1; -; Genomic_DNA.
DR   PIR; A38739; A38739.
DR   RefSeq; NP_999741.1; NM_214576.2.
DR   AlphaFoldDB; Q27287; -.
DR   SMR; Q27287; -.
DR   EnsemblMetazoa; XM_030974679; XP_030830539; LOC115919944.
DR   GeneID; 373378; -.
DR   KEGG; spu:373378; -.
DR   CTD; 373378; -.
DR   HOGENOM; CLU_2834403_0_0_1; -.
DR   PhylomeDB; Q27287; -.
DR   Proteomes; UP000007110; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR017980; Metalthion_4_echinoid/annelid.
DR   InterPro; IPR001396; Metalthion_4_echinoidea.
DR   InterPro; IPR017854; Metalthion_dom_sf.
DR   Pfam; PF05522; Metallothio_6; 1.
DR   PRINTS; PR00873; MTECHINOIDEA.
DR   SUPFAM; SSF57868; SSF57868; 2.
PE   2: Evidence at transcript level;
KW   Metal-binding; Metal-thiolate cluster; Reference proteome.
FT   CHAIN           1..65
FT                   /note="Metallothionein-B"
FT                   /id="PRO_0000197348"
SQ   SEQUENCE   65 AA;  6470 MW;  12E1C8064D9121A5 CRC64;
     MPDVKCVCCK EGNECACTGQ DCCTIGKCCK DGTCCGKCSN AACKTCADGC TCGSGCSCTE
     GNCPC