ID   MTC6_ASHGO              Reviewed;         450 AA.
AC   Q75AQ7;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2010, sequence version 2.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Maintenance of telomere capping protein 6;
DE   Flags: Precursor;
GN   Name=MTC6; OrderedLocusNames=ADL137W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: May be involved in telomere capping. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the MTC6 family. {ECO:0000305}.
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DR   EMBL; AE016817; AAS51783.2; -; Genomic_DNA.
DR   RefSeq; NP_983959.2; NM_209312.2.
DR   AlphaFoldDB; Q75AQ7; -.
DR   STRING; 33169.AAS51783; -.
DR   EnsemblFungi; AAS51783; AAS51783; AGOS_ADL137W.
DR   GeneID; 4620101; -.
DR   KEGG; ago:AGOS_ADL137W; -.
DR   eggNOG; ENOG502QVFP; Eukaryota.
DR   HOGENOM; CLU_033723_0_0_1; -.
DR   InParanoid; Q75AQ7; -.
DR   Proteomes; UP000000591; Chromosome IV.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR018378; C-type_lectin_CS.
PE   3: Inferred from homology;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..450
FT                   /note="Maintenance of telomere capping protein 6"
FT                   /id="PRO_0000407771"
FT   TOPO_DOM        19..397
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        398..418
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        419..450
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        204
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        247
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   450 AA;  49856 MW;  39F7A53DA90E1ED0 CRC64;
     MGSFLLCLLL VQLQWCLCSN VLDDLLQQTN IAFLSQQDVI GVIPVNQIPL VGVELCSMFE
     TVGDGQDTLA AMLQTGVQTL VMDIGYDEDA GGWQMCGRTS LSEGISTVSR QIERLFPTLY
     ANLVVLVLRG GAAEAHYEAL RDAIGRVGRW TYSAEKVKAT SPHLNSLLDD QEKRVLVVAL
     DDSLCEALGT VAFGPEDVAY VEGNDTIDCS EHTDSWSFIE REFHWTDVRE YVRLGCSPVI
     TGKSVANISE LEALVKVAQV WSWGAGEPAL TDANSEMQRC ASLGYDSATE RATWKSTSCR
     QNLPVLCQAV NDRYSWLVGT RNLRFDQLNM DSCPSGYKPS VPRTPLEQRE VERYLSEHHP
     SDGQYWIYLN SISVEKCWVV GGPETPCPYV ALVSTRNFAA MIVTSSILVL LLLVLIILLD
     LVRVPIQDNR RSWKRALGSY SKAETEGVPM