MTC6_CANDC
ID MTC6_CANDC Reviewed; 615 AA.
AC B9WE91;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 24-MAR-2009, sequence version 1.
DT 03-AUG-2022, entry version 43.
DE RecName: Full=Maintenance of telomere capping protein 6;
DE Flags: Precursor;
GN Name=MTC6; ORFNames=CD36_84990;
OS Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 /
OS NRRL Y-17841) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=573826;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841;
RX PubMed=19745113; DOI=10.1101/gr.097501.109;
RA Jackson A.P., Gamble J.A., Yeomans T., Moran G.P., Saunders D., Harris D.,
RA Aslett M., Barrell J.F., Butler G., Citiulo F., Coleman D.C.,
RA de Groot P.W.J., Goodwin T.J., Quail M.A., McQuillan J., Munro C.A.,
RA Pain A., Poulter R.T., Rajandream M.A., Renauld H., Spiering M.J.,
RA Tivey A., Gow N.A.R., Barrell B., Sullivan D.J., Berriman M.;
RT "Comparative genomics of the fungal pathogens Candida dubliniensis and
RT Candida albicans.";
RL Genome Res. 19:2231-2244(2009).
CC -!- FUNCTION: May be involved in telomere capping. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the MTC6 family. {ECO:0000305}.
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DR EMBL; FM992690; CAX43002.1; -; Genomic_DNA.
DR RefSeq; XP_002419408.1; XM_002419363.1.
DR AlphaFoldDB; B9WE91; -.
DR STRING; 42374.XP_002419408.1; -.
DR EnsemblFungi; CAX43002; CAX43002; CD36_84990.
DR GeneID; 8047231; -.
DR KEGG; cdu:CD36_84990; -.
DR CGD; CAL0000160876; Cd36_84990.
DR VEuPathDB; FungiDB:CD36_84990; -.
DR eggNOG; ENOG502QVFP; Eukaryota.
DR HOGENOM; CLU_033723_0_0_1; -.
DR OrthoDB; 618092at2759; -.
DR Proteomes; UP000002605; Chromosome 3.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Glycoprotein; Membrane; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..17
FT /evidence="ECO:0000255"
FT CHAIN 18..615
FT /note="Maintenance of telomere capping protein 6"
FT /id="PRO_0000407774"
FT TOPO_DOM 18..559
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 560..580
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 581..615
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 31
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 111
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 127
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 135
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 176
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 200
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 228
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 240
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 250
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 311
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 326
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 341
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 373
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 386
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 412
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 415
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 422
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 482
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 522
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 615 AA; 70269 MW; 1941DD097502FA7D CRC64;
MIGLLFVFSV LLSFSVGYIF PFSTSNGPTV NDTLQHAIRS QRDVSKPIPI DRVEFSGVSL
SSFFESEGYS SDSLSNLYGL LKENIAGVMI DLYWNEFTSK WQLCPAPFPN NITYTSSNRV
VDVSWNNRTY KCDPNLSTDD IMSILNNFIR DTNTDVEANF MHVMYNLKSI HYKKSNQTIN
LENAYKEKNS NFNVGMDTLN DTVSLLSSYI FTPLLLEQYQ SSSSKNANSS SSIRYIDSLN
ETQAIQKFYN QSTILMPSLQ TTLLTQYKRL MVHVISNDMA ESSRSYQISF SDKETIFFNN
VFPAMIGHTN NASADDFCYE LTHAYNGTDV NIMEFNRVSL NSTLRLIIDN DKTPFTTDSL
SKYVRCGYCP VFNSTQYSSQ KVTEGNSSII SQEFTSNLFW SWAPGQPSGP DNCTNCTRPV
TNYTSKYSEA SNGGSDEEEH SNNIAYKCVA LTENGWEVSN CYEKYLFACQ NKLSRNEWKL
DNYTKRNYFD LDDDDCPEGY FFSLPRSNIE MLSLMTTVKQ ENVSYPIWID LNDITVENCF
VSGGPYAQCP YQETVTTDKF VRMIAPSFVV AMVVLVLIFL EKVFRKTPIQ TNRKRYWKKA
IQEYYAKNDY EGVPS
