ID   MTC6_DEBHA              Reviewed;         617 AA.
AC   Q6BW46;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   04-NOV-2008, sequence version 2.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Maintenance of telomere capping protein 6;
DE   Flags: Precursor;
GN   Name=MTC6; OrderedLocusNames=DEHA2B14432g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: May be involved in telomere capping. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the MTC6 family. {ECO:0000305}.
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DR   EMBL; CR382134; CAG85584.2; -; Genomic_DNA.
DR   RefSeq; XP_457573.2; XM_457573.1.
DR   AlphaFoldDB; Q6BW46; -.
DR   STRING; 4959.XP_457573.2; -.
DR   EnsemblFungi; CAG85584; CAG85584; DEHA2B14432g.
DR   GeneID; 2913536; -.
DR   KEGG; dha:DEHA2B14432g; -.
DR   VEuPathDB; FungiDB:DEHA2B14432g; -.
DR   eggNOG; ENOG502QVFP; Eukaryota.
DR   HOGENOM; CLU_033723_0_0_1; -.
DR   InParanoid; Q6BW46; -.
DR   OMA; NLNESWY; -.
DR   OrthoDB; 618092at2759; -.
DR   Proteomes; UP000000599; Chromosome B.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..617
FT                   /note="Maintenance of telomere capping protein 6"
FT                   /id="PRO_0000407777"
FT   TOPO_DOM        23..561
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        562..582
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        583..617
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          409..435
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        113
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        179
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        204
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        208
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        242
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        279
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        327
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        341
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        347
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        363
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        411
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        524
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   617 AA;  69783 MW;  D1EE307C3F1A61EE CRC64;
     MISYTYITAL SILVLNVLNV ACTSVDDWPN LSPQIEIALR SQRDIGKYIS IDQVTGMGVS
     LNTLVFDKDG YTLDALNDVS TLLDVGVQTL MINLYWNEFT QKWQLCPAPF PANISSDITT
     SKELYWDGRT YKCEASLTVD SLVRTINTYL AETNTNIKVN MVHLLFHLKS IRIDPPSGNV
     SSSEIKDYIS TFQPTDSHFV ALNNATLNDT VSSFGTSLFT PSDLSSYRKS NYRKGDKVGF
     YNETRKSFPN LNTFLLLDYK RVMTTVIAND LVKSQYTYNV TSSDKKSVFL EGSGVDTTVA
     SLSDPDAVSQ CNELIHYNQD NIEVFDNISL KEHFRIVVDD NGTSFTNVTF SDFVRCGFSP
     ILNASYYNVY NDEEGVSEID GSLSDIVDNF IPLSFWSWAE NQLIEPNRGL NISDSTDTDN
     DEERDDNDND DPLVRRDMDY KSSHTAFKCV VLDENGWKVS DCYSRQPIAC QKSGSPNDWH
     IDVKTKREYF TAYKDDSCPD DYNFGIPSSS IEMLALMSYI ERENISYPVW IDMNDITVPD
     CFVTGGPYAT CPYQMTVTRL KLAGLIAPSF IVAVVILALI LCEKIFRTNP IQSNRKRHWK
     KAINKYVEKY DYEGVPS