MTC6_YARLI
ID MTC6_YARLI Reviewed; 685 AA.
AC Q6CEA4;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 25-MAY-2022, entry version 62.
DE RecName: Full=Maintenance of telomere capping protein 6;
DE Flags: Precursor;
GN Name=MTC6; OrderedLocusNames=YALI0B17248g;
OS Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Dipodascaceae; Yarrowia.
OX NCBI_TaxID=284591;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CLIB 122 / E 150;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: May be involved in telomere capping. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the MTC6 family. {ECO:0000305}.
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DR EMBL; CR382128; CAG83261.1; -; Genomic_DNA.
DR RefSeq; XP_501008.1; XM_501008.1.
DR AlphaFoldDB; Q6CEA4; -.
DR STRING; 4952.CAG83261; -.
DR EnsemblFungi; CAG83261; CAG83261; YALI0_B17248g.
DR GeneID; 2906681; -.
DR KEGG; yli:YALI0B17248g; -.
DR VEuPathDB; FungiDB:YALI0_B17248g; -.
DR HOGENOM; CLU_033723_0_0_1; -.
DR InParanoid; Q6CEA4; -.
DR OMA; NLNESWY; -.
DR Proteomes; UP000001300; Chromosome B.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..685
FT /note="Maintenance of telomere capping protein 6"
FT /id="PRO_0000407784"
FT TOPO_DOM 23..633
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 634..654
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 655..685
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 201..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 238..295
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 309..328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..324
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 75
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 163
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 178
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 205
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 235
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 254
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 258
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 264
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 412
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 432
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 448
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 478
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 685 AA; 75974 MW; 22C29327582D4690 CRC64;
MVWLWTLPWT FILVALIPLA TAKSPDVHHS LQQLKKRDDD SLRDENCQAW IAPVWPGMSH
MMVAATRAER DVSYNVSIDQ LTYKGAELTP LVFNKYGYTQ DGIFKSMDLL KSGMTSLGLD
VYWNNKEQYW QLCPVIFPSS AEPGTPVLLQ RRLTTDIVTC DQNATLSYFL AALSNHVNVT
DNNLDVDLIS LKLNLRTVET PIQSNSSSQR QKRQFRETST SVTQLASSVL SSLLNASKTT
RMESTGSFSN SDSNSSSNSS RMSNSTESTR TTSSTESASS TSTTPSTYTT GPQMLGNIVG
SSYIGPRLYT PKDLHRDREA EPPRTYDYQG LSNRGFPLAH YILLEMKARV MVSISQNDQP
DGYGWGSADQ DVIFTKQALL GSSDPENTNE NIAYENLQEC IRLDPQFLQS INLTGAASWR
TYSSTQQDPI SNVSFQEFIN CGLSPSINNT LAPGETLQGL MTESLWSWAE DEPSKCHNES
VTRTQDRNTG LVAWNCAVLM PDGWHVANCY DTHYPLCRQG ELAYNWAVGT QKVNYFDTAQ
EKNICPPGYT FSLPRTALQN IAAKITVRGV SGKTRVYKGG DTTDPDSYDT IDYGNTAFPV
WIDLNSISQE DCWVSGGPTA RCPYRTVQSH SVSVALLTVA SAVCAGVAAA IILLQMDTQP
IKKNSGRWRR LMSNFKKSEY ESVPA
