MTC7_YEAST
ID MTC7_YEAST Reviewed; 139 AA.
AC P32633; D3DLL6;
DT 01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1993, sequence version 1.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Maintenance of telomere capping protein 7;
GN Name=MTC7; OrderedLocusNames=YEL033W; ORFNames=SYGP-ORF22;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169868;
RA Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E.,
RA Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E.,
RA Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S.,
RA Hyman R.W., Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D.,
RA Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X.,
RA Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y.,
RA Botstein D., Davis R.W.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome V.";
RL Nature 387:78-81(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP FUNCTION.
RX PubMed=18845848; DOI=10.1534/genetics.108.092577;
RA Addinall S.G., Downey M., Yu M., Zubko M.K., Dewar J., Leake A.,
RA Hallinan J., Shaw O., James K., Wilkinson D.J., Wipat A., Durocher D.,
RA Lydall D.;
RT "A genomewide suppressor and enhancer analysis of cdc13-1 reveals varied
RT cellular processes influencing telomere capping in Saccharomyces
RT cerevisiae.";
RL Genetics 180:2251-2266(2008).
CC -!- FUNCTION: May be involved in telomere capping.
CC {ECO:0000269|PubMed:18845848}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; U18779; AAB65009.1; -; Genomic_DNA.
DR EMBL; BK006939; DAA07620.1; -; Genomic_DNA.
DR PIR; S30850; S30850.
DR RefSeq; NP_010881.1; NM_001178848.1.
DR AlphaFoldDB; P32633; -.
DR SMR; P32633; -.
DR BioGRID; 300943; 5.
DR IntAct; P32633; 1.
DR STRING; 4932.YEL033W; -.
DR PaxDb; P32633; -.
DR EnsemblFungi; YEL033W_mRNA; YEL033W; YEL033W.
DR GeneID; 856678; -.
DR KEGG; sce:YEL033W; -.
DR SGD; S000000759; MTC7.
DR VEuPathDB; FungiDB:YEL033W; -.
DR HOGENOM; CLU_1897411_0_0_1; -.
DR BioCyc; YEAST:G3O-30155-MON; -.
DR ChiTaRS; MTC7; yeast.
DR PRO; PR:P32633; -.
DR Proteomes; UP000002311; Chromosome V.
DR RNAct; P32633; protein.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE 4: Predicted;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..139
FT /note="Maintenance of telomere capping protein 7"
FT /id="PRO_0000202608"
FT TRANSMEM 13..33
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 94..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 139 AA; 16094 MW; 301A1E922A71D79A CRC64;
MKKEKKTPTP LPSHHVLFAE PGFFLCNFFF VLLKHTQINP FFYFLFILLF IIYIAIIYFV
FIRISHFSFS LCRQCNSLGR MIFMCAYLPA ASSRSVANPA LPPQKKKKKK KKGTLRTGEV
EEQAKGNISF DLCGKQNFQ
