ID   MTCY_LEUME              Reviewed;          61 AA.
AC   P38577;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 2.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Bacteriocin mesentericin Y105;
DE   Flags: Precursor;
GN   Name=mesY;
OS   Leuconostoc mesenteroides.
OG   Plasmid pHY30.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Leuconostoc.
OX   NCBI_TaxID=1245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Y105;
RX   PubMed=7551032; DOI=10.1099/13500872-141-7-1637;
RA   Fremaux C., Hechard A., Cenatiempo Y.;
RT   "Mesentericin Y105 gene clusters in Leuconostoc mesenteroides Y105.";
RL   Microbiology 141:1637-1645(1995).
RN   [2]
RP   PROTEIN SEQUENCE OF 25-60.
RC   STRAIN=Y105;
RX   PubMed=1487737; DOI=10.1099/00221287-138-12-2725;
RA   Hechard Y., Derijard B., Letellier F., Cenatiempo Y.;
RT   "Characterization and purification of mesentericin Y105, an anti-Listeria
RT   bacteriocin from Leuconostoc mesenteroides.";
RL   J. Gen. Microbiol. 138:2725-2731(1992).
CC   -!- FUNCTION: Bacteriocin active against Listeria monocytogenes.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the bacteriocin class IIA/YGNGV family.
CC       {ECO:0000305}.
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DR   EMBL; X81803; CAA57405.1; -; Genomic_DNA.
DR   PIR; S52208; S52208.
DR   AlphaFoldDB; P38577; -.
DR   TCDB; 1.C.24.1.5; the pediocin (pediocin) family.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.130; -; 1.
DR   InterPro; IPR002633; Bacteriocin_IIa.
DR   InterPro; IPR023384; Bacteriocin_IIa_CS.
DR   InterPro; IPR023388; Bacteriocin_IIa_dom_sf.
DR   Pfam; PF01721; Bacteriocin_II; 1.
DR   PROSITE; PS60030; BACTERIOCIN_IIA; 1.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Bacteriocin; Direct protein sequencing;
KW   Disulfide bond; Plasmid; Secreted; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000269|PubMed:1487737"
FT   CHAIN           25..61
FT                   /note="Bacteriocin mesentericin Y105"
FT                   /id="PRO_0000002744"
FT   DISULFID        33..38
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   61 AA;  6548 MW;  C3CB768902F8CB59 CRC64;
     MTNMKSVEAY QQLDNQNLKK VVGGKYYGNG VHCTKSGCSV NWGEAASAGI HRLANGGNGF
     W