ID   MTEF1_ARATH             Reviewed;         284 AA.
AC   Q84X53; O80618;
DT   11-MAY-2016, integrated into UniProtKB/Swiss-Prot.
DT   11-MAY-2016, sequence version 2.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Transcription termination factor MTEF1, chloroplastic {ECO:0000305};
DE   AltName: Full=Mitochondrial transcription termination factor 1 {ECO:0000303|PubMed:23087700};
DE   AltName: Full=Protein EMBRYO DEFECTIVE 93 {ECO:0000305};
DE   AltName: Full=Protein SINGLET OXYGEN-LINKED DEATH ACTIVATOR 10 {ECO:0000303|PubMed:19563435};
DE   Flags: Precursor;
GN   Name=MTERF1 {ECO:0000303|PubMed:23087700};
GN   Synonyms=EMB93 {ECO:0000305}, SOLDAT10 {ECO:0000303|PubMed:19563435};
GN   OrderedLocusNames=At2g03050 {ECO:0000312|Araport:AT2G03050};
GN   ORFNames=T17M13.22 {ECO:0000312|EMBL:AAT69165.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2-284.
RC   STRAIN=cv. Columbia;
RX   PubMed=12481096; DOI=10.1104/pp.010207;
RA   Xiao Y.-L., Malik M., Whitelaw C.A., Town C.D.;
RT   "Cloning and sequencing of cDNAs for hypothetical genes from chromosome 2
RT   of Arabidopsis.";
RL   Plant Physiol. 130:2118-2128(2002).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 2-284.
RC   STRAIN=cv. Columbia;
RA   Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA   Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   FUNCTION, AND DISRUPTION PHENOTYPE.
RX   PubMed=12324593; DOI=10.2307/3869284;
RA   Errampalli D., Patton D., Castle L., Mickelson L., Hansen K., Schnall J.,
RA   Feldmann K., Meinke D.;
RT   "Embryonic lethals and T-DNA insertional mutagenesis in Arabidopsis.";
RL   Plant Cell 3:149-157(1991).
RN   [6]
RP   FUNCTION, SUBCELLULAR LOCATION, AND DISRUPTION PHENOTYPE.
RX   PubMed=19563435; DOI=10.1111/j.1365-313x.2009.03965.x;
RA   Meskauskiene R., Wuersch M., Laloi C., Vidi P.A., Coll N.S., Kessler F.,
RA   Baruah A., Kim C., Apel K.;
RT   "A mutation in the Arabidopsis mTERF-related plastid protein SOLDAT10
RT   activates retrograde signaling and suppresses (1)O(2)-induced cell death.";
RL   Plant J. 60:399-410(2009).
RN   [7]
RP   SUBCELLULAR LOCATION.
RX   PubMed=21464319; DOI=10.1073/pnas.1103442108;
RA   Babiychuk E., Vandepoele K., Wissing J., Garcia-Diaz M., De Rycke R.,
RA   Akbari H., Joubes J., Beeckman T., Jaensch L., Frentzen M.,
RA   Van Montagu M.C., Kushnir S.;
RT   "Plastid gene expression and plant development require a plastidic protein
RT   of the mitochondrial transcription termination factor family.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:6674-6679(2011).
RN   [8]
RP   GENE FAMILY.
RX   PubMed=23087700; DOI=10.3389/fpls.2012.00233;
RA   Kleine T.;
RT   "Arabidopsis thaliana mTERF proteins: evolution and functional
RT   classification.";
RL   Front. Plant Sci. 3:233-233(2012).
CC   -!- FUNCTION: Transcription termination factor required for plastid-
CC       specific rRNA accumulation and protein synthesis in plastids
CC       (PubMed:19563435). Essential for embryogenesis (PubMed:12324593,
CC       PubMed:19563435). {ECO:0000269|PubMed:12324593,
CC       ECO:0000269|PubMed:19563435}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC       {ECO:0000269|PubMed:19563435, ECO:0000269|PubMed:21464319}.
CC   -!- DISRUPTION PHENOTYPE: Albino seed and embryo defective when homozygous
CC       (PubMed:12324593, PubMed:19563435). Developmental arrest of the embryo
CC       from globular to mature stages (PubMed:12324593).
CC       {ECO:0000269|PubMed:12324593, ECO:0000269|PubMed:19563435}.
CC   -!- SIMILARITY: Belongs to the mTERF family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AEC05659.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AC004138; AAC32923.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC05659.1; ALT_INIT; Genomic_DNA.
DR   EMBL; CP002685; ANM62290.1; -; Genomic_DNA.
DR   EMBL; AY219044; AAO37134.1; -; mRNA.
DR   EMBL; AY649248; AAT69165.1; -; Genomic_DNA.
DR   PIR; G84443; G84443.
DR   RefSeq; NP_001324457.1; NM_001335150.1.
DR   RefSeq; NP_178405.2; NM_126357.2.
DR   AlphaFoldDB; Q84X53; -.
DR   SMR; Q84X53; -.
DR   IntAct; Q84X53; 7.
DR   STRING; 3702.AT2G03050.1; -.
DR   PaxDb; Q84X53; -.
DR   PRIDE; Q84X53; -.
DR   ProteomicsDB; 250806; -.
DR   EnsemblPlants; AT2G03050.2; AT2G03050.2; AT2G03050.
DR   GeneID; 814834; -.
DR   Gramene; AT2G03050.2; AT2G03050.2; AT2G03050.
DR   KEGG; ath:AT2G03050; -.
DR   Araport; AT2G03050; -.
DR   TAIR; locus:2056745; AT2G03050.
DR   eggNOG; KOG1267; Eukaryota.
DR   HOGENOM; CLU_032090_0_1_1; -.
DR   InParanoid; Q84X53; -.
DR   OrthoDB; 1294087at2759; -.
DR   PRO; PR:Q84X53; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q84X53; baseline and differential.
DR   GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:InterPro.
DR   GO; GO:0071452; P:cellular response to singlet oxygen; IGI:TAIR.
DR   GO; GO:0009658; P:chloroplast organization; IMP:UniProtKB.
DR   GO; GO:0032502; P:developmental process; IBA:GO_Central.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-KW.
DR   GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.25.70.10; -; 1.
DR   InterPro; IPR003690; MTERF.
DR   InterPro; IPR038538; MTERF_sf.
DR   PANTHER; PTHR13068; PTHR13068; 1.
DR   Pfam; PF02536; mTERF; 2.
DR   SMART; SM00733; Mterf; 5.
PE   2: Evidence at transcript level;
KW   Chloroplast; Plastid; Reference proteome; Transcription;
KW   Transcription regulation; Transcription termination; Transit peptide.
FT   TRANSIT         1..22
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..284
FT                   /note="Transcription termination factor MTEF1,
FT                   chloroplastic"
FT                   /id="PRO_0000436195"
SQ   SEQUENCE   284 AA;  32391 MW;  C70D2AE42132B515 CRC64;
     MMIARCSLFP PPCFSAVRIR CFAGETSDTG ILFREKLIYL QDLNVDPHKA LRVNPSLRSA
     PISSVVSVET LLSSTGLSRP AVGRILDMFP DLLTSDPESE ILPVLRFLSN EISISEQDIP
     KSISRCPRLL ISSVDYQLRP ALTFLKTLGF VGRDTITSRN TVLLVSNVER TLIPKIEYLE
     EGLGFTREEV AKMVVRSPAL LTYSVDNNLV PKVEFFIEEM RGDVKELKRF PQYFSFSLER
     KIKPRHRLLK EHGILMPLSE MLKVSDGQFN HWLLELRLRS AERR