ID   MTEF2_PONAB             Reviewed;         385 AA.
AC   Q5R6G1;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Transcription termination factor 2, mitochondrial;
DE   AltName: Full=Mitochondrial transcription termination factor 2;
DE            Short=mTERF2;
DE   AltName: Full=mTERF domain-containing protein 3, mitochondrial;
DE   Flags: Precursor;
GN   Name=MTERF2; Synonyms=MTERFD3;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Binds mitochondrial DNA and plays a role in the regulation of
CC       transcription of mitochondrial mRNA and rRNA species.
CC       {ECO:0000250|UniProtKB:Q49AM1}.
CC   -!- SUBUNIT: Monomer. {ECO:0000250|UniProtKB:Q49AM1}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix, mitochondrion nucleoid
CC       {ECO:0000250|UniProtKB:Q8BKY8}.
CC   -!- SIMILARITY: Belongs to the mTERF family. {ECO:0000305}.
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DR   EMBL; CR860529; CAH92655.1; -; mRNA.
DR   RefSeq; NP_001126554.1; NM_001133082.1.
DR   RefSeq; XP_009246447.1; XM_009248172.1.
DR   RefSeq; XP_009246448.1; XM_009248173.1.
DR   RefSeq; XP_009246449.1; XM_009248174.1.
DR   AlphaFoldDB; Q5R6G1; -.
DR   SMR; Q5R6G1; -.
DR   STRING; 9601.ENSPPYP00000005603; -.
DR   Ensembl; ENSPPYT00000005818; ENSPPYP00000005603; ENSPPYG00000004910.
DR   Ensembl; ENSPPYT00000059661; ENSPPYP00000030130; ENSPPYG00000004910.
DR   GeneID; 100173545; -.
DR   KEGG; pon:100173545; -.
DR   CTD; 80298; -.
DR   eggNOG; KOG1267; Eukaryota.
DR   GeneTree; ENSGT00530000063817; -.
DR   HOGENOM; CLU_058644_0_0_1; -.
DR   InParanoid; Q5R6G1; -.
DR   OMA; LWMSVCP; -.
DR   OrthoDB; 1103140at2759; -.
DR   TreeFam; TF330821; -.
DR   Proteomes; UP000001595; Chromosome 12.
DR   GO; GO:0042645; C:mitochondrial nucleoid; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.25.70.10; -; 1.
DR   InterPro; IPR003690; MTERF.
DR   InterPro; IPR038538; MTERF_sf.
DR   PANTHER; PTHR15437; PTHR15437; 1.
DR   Pfam; PF02536; mTERF; 1.
DR   SMART; SM00733; Mterf; 5.
PE   2: Evidence at transcript level;
KW   Mitochondrion; Mitochondrion nucleoid; Reference proteome; Transcription;
KW   Transcription regulation; Transit peptide.
FT   TRANSIT         1..35
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000250|UniProtKB:Q49AM1"
FT   CHAIN           36..385
FT                   /note="Transcription termination factor 2, mitochondrial"
FT                   /id="PRO_0000255466"
SQ   SEQUENCE   385 AA;  44553 MW;  21BCE9EB86EC561A CRC64;
     MLWKLLLRSQ SCRLCSFRKM RSPPKYRPFL ACFTYTTDRQ SSKENTRTVE KLYKCSVDIR
     KIRRLKGWVL LEDETYVEEI ANILQELGAD ETAVANILER CPEAIVCRPT AVNTQRKLWQ
     LVCKNEEELI KLIEQFPESF FTIKDQENQK LNVQFFQELG LKNVVISRLL TAASNVFHNP
     VEKNKQMVRI LQESYLNVGG SEANMKVWLL KLLSQNPFIL LNSPTAIKET LEFLQEQGFT
     SFEILQLLSK LKGFLFQLCP RSIQNSISFS KNAFKCTDHD LKQLVLKCPA LLYYSVPVLE
     ERMQGLLREG ISIAQIRETP MVLELTPQIV QYRIRKLNSL GYRIKDGHLA NLNGSKKEFE
     ANFGKIQAKK VRPLFNPVAP LNVEE