ID   MTEF3_CHICK             Reviewed;         405 AA.
AC   Q5ZJC8;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Transcription termination factor 3, mitochondrial;
DE   AltName: Full=mTERF domain-containing protein 1, mitochondrial;
DE   Flags: Precursor;
GN   Name=MTERF3; Synonyms=MTERFD1; OrderedLocusNames=CGI-12;
GN   ORFNames=RCJMB04_19e6;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Binds promoter DNA and regulates initiation of transcription.
CC       Required for normal mitochondrial transcription, and for normal
CC       assembly of mitochondrial respiratory complexes. Required for normal
CC       mitochondrial function (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- DOMAIN: Contains about seven structural repeats of about 35 residues,
CC       where each repeat contains three helices. The repeats form a
CC       superhelical structure with a solenoid shape (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the mTERF family. {ECO:0000305}.
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DR   EMBL; AJ720506; CAG32165.1; -; mRNA.
DR   RefSeq; NP_001006348.1; NM_001006348.1.
DR   AlphaFoldDB; Q5ZJC8; -.
DR   SMR; Q5ZJC8; -.
DR   STRING; 9031.ENSGALP00000025725; -.
DR   PaxDb; Q5ZJC8; -.
DR   GeneID; 420237; -.
DR   KEGG; gga:420237; -.
DR   CTD; 51001; -.
DR   VEuPathDB; HostDB:geneid_420237; -.
DR   eggNOG; KOG1267; Eukaryota.
DR   InParanoid; Q5ZJC8; -.
DR   OrthoDB; 1294087at2759; -.
DR   PhylomeDB; Q5ZJC8; -.
DR   PRO; PR:Q5ZJC8; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; ISS:UniProtKB.
DR   GO; GO:0061668; P:mitochondrial ribosome assembly; IBA:GO_Central.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   Gene3D; 1.25.70.10; -; 1.
DR   InterPro; IPR003690; MTERF.
DR   InterPro; IPR038538; MTERF_sf.
DR   PANTHER; PTHR13068; PTHR13068; 1.
DR   Pfam; PF02536; mTERF; 1.
DR   SMART; SM00733; Mterf; 5.
PE   2: Evidence at transcript level;
KW   Mitochondrion; Reference proteome; Transcription; Transcription regulation;
KW   Transit peptide.
FT   TRANSIT         1..64
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           65..405
FT                   /note="Transcription termination factor 3, mitochondrial"
FT                   /id="PRO_0000255460"
SQ   SEQUENCE   405 AA;  45633 MW;  AFE8CBAFDA438632 CRC64;
     MAVWARQVAR CGWLRAAGLL GLRSRSGAAR ACCGAAPLPA LLSGHRLPPW RLRVSVDYAQ
     PSRAKGEACA PRSSLPVAVK QEQAAPETVS DLSAAKLCED WDDVPPSSAL EEISEEEAVK
     IIADPLLPPQ SSTLRDYVDH SETLTKLVHL GVDLSQVEKR QKAGQLLLTL DFEKDITKIL
     LFLKDVGIED NQLGPFLTKN PYILGEELEA LETRVAYLKS KKFGNAEITQ MVSRAPYLLL
     FSVERLDNRL GFFKNELGLS VKKTKDLVIR FPRLLTGKLE PVKENLQVCQ VEFGFERNEV
     QQIAFKTPKI LTASKKRLRQ TFDYLHNIMG IPHNMLTRFP QVFNSKLLRI KERHMFLIFL
     GRAQYDPTKP SYISLDQLVS LPDEVFCTEI AKASMQDFEK FLKTI