ID   MTEF4_MAIZE             Reviewed;         494 AA.
AC   B6TGN4;
DT   25-OCT-2017, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Transcription termination factor MTERF4, chloroplastic {ECO:0000305};
DE   AltName: Full=Mitochondrial transcription termination factor 4 {ECO:0000303|PubMed:24500208};
DE   Flags: Precursor;
GN   Name=MTERF4 {ECO:0000303|PubMed:24500208};
GN   ORFNames=ZEAMMB73_Zm00001d010340 {ECO:0000312|EMBL:AQK93897.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. B73;
RX   PubMed=19965430; DOI=10.1126/science.1178534;
RA   Schnable P.S., Ware D., Fulton R.S., Stein J.C., Wei F., Pasternak S.,
RA   Liang C., Zhang J., Fulton L., Graves T.A., Minx P., Reily A.D.,
RA   Courtney L., Kruchowski S.S., Tomlinson C., Strong C., Delehaunty K.,
RA   Fronick C., Courtney B., Rock S.M., Belter E., Du F., Kim K., Abbott R.M.,
RA   Cotton M., Levy A., Marchetto P., Ochoa K., Jackson S.M., Gillam B.,
RA   Chen W., Yan L., Higginbotham J., Cardenas M., Waligorski J., Applebaum E.,
RA   Phelps L., Falcone J., Kanchi K., Thane T., Scimone A., Thane N., Henke J.,
RA   Wang T., Ruppert J., Shah N., Rotter K., Hodges J., Ingenthron E.,
RA   Cordes M., Kohlberg S., Sgro J., Delgado B., Mead K., Chinwalla A.,
RA   Leonard S., Crouse K., Collura K., Kudrna D., Currie J., He R.,
RA   Angelova A., Rajasekar S., Mueller T., Lomeli R., Scara G., Ko A.,
RA   Delaney K., Wissotski M., Lopez G., Campos D., Braidotti M., Ashley E.,
RA   Golser W., Kim H., Lee S., Lin J., Dujmic Z., Kim W., Talag J., Zuccolo A.,
RA   Fan C., Sebastian A., Kramer M., Spiegel L., Nascimento L., Zutavern T.,
RA   Miller B., Ambroise C., Muller S., Spooner W., Narechania A., Ren L.,
RA   Wei S., Kumari S., Faga B., Levy M.J., McMahan L., Van Buren P.,
RA   Vaughn M.W., Ying K., Yeh C.-T., Emrich S.J., Jia Y., Kalyanaraman A.,
RA   Hsia A.-P., Barbazuk W.B., Baucom R.S., Brutnell T.P., Carpita N.C.,
RA   Chaparro C., Chia J.-M., Deragon J.-M., Estill J.C., Fu Y., Jeddeloh J.A.,
RA   Han Y., Lee H., Li P., Lisch D.R., Liu S., Liu Z., Nagel D.H., McCann M.C.,
RA   SanMiguel P., Myers A.M., Nettleton D., Nguyen J., Penning B.W.,
RA   Ponnala L., Schneider K.L., Schwartz D.C., Sharma A., Soderlund C.,
RA   Springer N.M., Sun Q., Wang H., Waterman M., Westerman R., Wolfgruber T.K.,
RA   Yang L., Yu Y., Zhang L., Zhou S., Zhu Q., Bennetzen J.L., Dawe R.K.,
RA   Jiang J., Jiang N., Presting G.G., Wessler S.R., Aluru S.,
RA   Martienssen R.A., Clifton S.W., McCombie W.R., Wing R.A., Wilson R.K.;
RT   "The B73 maize genome: complexity, diversity, and dynamics.";
RL   Science 326:1112-1115(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=18937034; DOI=10.1007/s11103-008-9415-4;
RA   Alexandrov N.N., Brover V.V., Freidin S., Troukhan M.E., Tatarinova T.V.,
RA   Zhang H., Swaller T.J., Lu Y.-P., Bouck J., Flavell R.B., Feldmann K.A.;
RT   "Insights into corn genes derived from large-scale cDNA sequencing.";
RL   Plant Mol. Biol. 69:179-194(2009).
RN   [3]
RP   FUNCTION, SUBCELLULAR LOCATION, AND DISRUPTION PHENOTYPE.
RX   PubMed=24500208; DOI=10.1093/nar/gku112;
RA   Hammani K., Barkan A.;
RT   "An mTERF domain protein functions in group II intron splicing in maize
RT   chloroplasts.";
RL   Nucleic Acids Res. 42:5033-5042(2014).
CC   -!- FUNCTION: Transcription termination factor required for processing and
CC       steady-state levels of plastid transcripts. Required for splicing of
CC       the chloroplastic group II intron. Required for the accumulation of 16S
CC       and 23S ribosomes. {ECO:0000269|PubMed:24500208}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast stroma
CC       {ECO:0000269|PubMed:24500208}.
CC   -!- DISRUPTION PHENOTYPE: Seedling lethality.
CC       {ECO:0000269|PubMed:24500208}.
CC   -!- SIMILARITY: Belongs to the mTERF family. {ECO:0000305}.
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DR   EMBL; CM000784; AQK93897.1; -; Genomic_DNA.
DR   EMBL; EU964149; ACG36267.1; -; mRNA.
DR   RefSeq; NP_001149660.1; NM_001156188.1.
DR   AlphaFoldDB; B6TGN4; -.
DR   SMR; B6TGN4; -.
DR   STRING; 4577.GRMZM2G029933_P01; -.
DR   PaxDb; B6TGN4; -.
DR   PRIDE; B6TGN4; -.
DR   EnsemblPlants; Zm00001eb349900_T001; Zm00001eb349900_P001; Zm00001eb349900.
DR   EnsemblPlants; Zm00001eb349900_T003; Zm00001eb349900_P003; Zm00001eb349900.
DR   Gramene; Zm00001eb349900_T001; Zm00001eb349900_P001; Zm00001eb349900.
DR   Gramene; Zm00001eb349900_T003; Zm00001eb349900_P003; Zm00001eb349900.
DR   eggNOG; KOG1267; Eukaryota.
DR   HOGENOM; CLU_024229_1_1_1; -.
DR   OMA; TIDMEEM; -.
DR   Proteomes; UP000007305; Chromosome 8.
DR   ExpressionAtlas; B6TGN4; baseline and differential.
DR   GO; GO:0009570; C:chloroplast stroma; IDA:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:InterPro.
DR   GO; GO:0032502; P:developmental process; IBA:GO_Central.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0042254; P:ribosome biogenesis; IMP:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IMP:UniProtKB.
DR   Gene3D; 1.25.70.10; -; 2.
DR   InterPro; IPR003690; MTERF.
DR   InterPro; IPR038538; MTERF_sf.
DR   PANTHER; PTHR13068; PTHR13068; 1.
DR   Pfam; PF02536; mTERF; 1.
DR   SMART; SM00733; Mterf; 9.
PE   2: Evidence at transcript level;
KW   Chloroplast; Plastid; Reference proteome; Transcription;
KW   Transcription regulation; Transcription termination; Transit peptide.
FT   TRANSIT         1..54
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           55..494
FT                   /note="Transcription termination factor MTERF4,
FT                   chloroplastic"
FT                   /id="PRO_0000441881"
FT   REGION          32..61
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          457..494
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        470..494
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   494 AA;  55231 MW;  0672FA4A0AAAC16F CRC64;
     MMKSLLFSAH PTSLLLPAPR LRRLLRLRAA SSASASAPPR ADRRSPGTPS RRPSSSLYAR
     PSLLDMERDR ATRRADVDAF LTSLGVDPGE LAGLELPVTV DVMRERAEFL GSLGLTQEDL
     AAYPLALGCS VRKNMVPVLD YLGKLGVRRD ALPDLLRRYP QVLHASVVVD LAPVVKYLQG
     MDVRPTDVPR VLERYPELLG FKLEGTMSTS VAYLVGIGVG RRQVGSVITR FPEVLGMRVG
     KIIKPFVEHL EGIGLQRLAI ARIIEKKPYV LGFGLQEKVK PNIEALVDIG VRKEALASIV
     MQYPDVLGLE LRDKLVAQQS LFESSILVSR EDFGRVLERM PQAISLGRAA VLKHVNFLTA
     CGFMLSQVSK MVVACPQLLA LNIDIMRMNF EYFKNEMERD LEELVEFPAF FTYGIESTVR
     PRHEMVSRKG LTCSLAWLLN CSDAKFDERM KYDTIGVEEM EREDSSDMNA SVDEVESEEY
     EDSDYGDSDD EFVR