MTEF8_ARATH
ID MTEF8_ARATH Reviewed; 500 AA.
AC Q9FK23; Q8L9V2;
DT 11-MAY-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Transcription termination factor MTERF8, chloroplastic {ECO:0000305};
DE AltName: Full=Mitochondrial transcription termination factor 8 {ECO:0000303|PubMed:23087700};
DE AltName: Full=Protein PLASTID TRANSCRIPTIONALLY ACTIVE 15 {ECO:0000303|PubMed:16326926};
DE Flags: Precursor;
GN Name=MTERF8 {ECO:0000303|PubMed:23087700};
GN Synonyms=PTAC15 {ECO:0000303|PubMed:16326926};
GN OrderedLocusNames=At5g54180 {ECO:0000312|Araport:AT5G54180};
GN ORFNames=K18G13.5 {ECO:0000312|EMBL:BAB11580.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9734815; DOI=10.1093/dnares/5.3.203;
RA Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence
RT features of the regions of 1,367,185 bp covered by 19 physically assigned
RT P1 and TAC clones.";
RL DNA Res. 5:203-216(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY, FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=16326926; DOI=10.1105/tpc.105.036392;
RA Pfalz J., Liere K., Kandlbinder A., Dietz K.-J., Oelmueller R.;
RT "pTAC2, -6, and -12 are components of the transcriptionally active plastid
RT chromosome that are required for plastid gene expression.";
RL Plant Cell 18:176-197(2006).
RN [6]
RP SUBCELLULAR LOCATION.
RX PubMed=21464319; DOI=10.1073/pnas.1103442108;
RA Babiychuk E., Vandepoele K., Wissing J., Garcia-Diaz M., De Rycke R.,
RA Akbari H., Joubes J., Beeckman T., Jaensch L., Frentzen M.,
RA Van Montagu M.C., Kushnir S.;
RT "Plastid gene expression and plant development require a plastidic protein
RT of the mitochondrial transcription termination factor family.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:6674-6679(2011).
RN [7]
RP GENE FAMILY.
RX PubMed=23087700; DOI=10.3389/fpls.2012.00233;
RA Kleine T.;
RT "Arabidopsis thaliana mTERF proteins: evolution and functional
RT classification.";
RL Front. Plant Sci. 3:233-233(2012).
CC -!- FUNCTION: Transcription termination factor that is transcriptionally
CC active in chloroplasts. {ECO:0000269|PubMed:16326926}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC {ECO:0000269|PubMed:16326926, ECO:0000269|PubMed:21464319}.
CC -!- SIMILARITY: Belongs to the mTERF family. {ECO:0000305}.
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DR EMBL; AB013387; BAB11580.1; -; Genomic_DNA.
DR EMBL; CP002688; AED96463.1; -; Genomic_DNA.
DR EMBL; AY081343; AAL91232.1; -; mRNA.
DR EMBL; BT000254; AAN15573.1; -; mRNA.
DR EMBL; AY088205; AAM65747.1; -; mRNA.
DR RefSeq; NP_200229.1; NM_124798.4.
DR AlphaFoldDB; Q9FK23; -.
DR SMR; Q9FK23; -.
DR IntAct; Q9FK23; 1.
DR MINT; Q9FK23; -.
DR STRING; 3702.AT5G54180.1; -.
DR iPTMnet; Q9FK23; -.
DR PaxDb; Q9FK23; -.
DR PRIDE; Q9FK23; -.
DR ProteomicsDB; 250967; -.
DR EnsemblPlants; AT5G54180.1; AT5G54180.1; AT5G54180.
DR GeneID; 835506; -.
DR Gramene; AT5G54180.1; AT5G54180.1; AT5G54180.
DR KEGG; ath:AT5G54180; -.
DR Araport; AT5G54180; -.
DR TAIR; locus:2153433; AT5G54180.
DR eggNOG; KOG1267; Eukaryota.
DR HOGENOM; CLU_547927_0_0_1; -.
DR InParanoid; Q9FK23; -.
DR OMA; QILQYNH; -.
DR OrthoDB; 768343at2759; -.
DR PhylomeDB; Q9FK23; -.
DR PRO; PR:Q9FK23; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FK23; baseline and differential.
DR GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR GO; GO:0042644; C:chloroplast nucleoid; HDA:TAIR.
DR GO; GO:0005739; C:mitochondrion; IEA:GOC.
DR GO; GO:0003690; F:double-stranded DNA binding; IEA:InterPro.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR GO; GO:0009658; P:chloroplast organization; IBA:GO_Central.
DR GO; GO:0032502; P:developmental process; IBA:GO_Central.
DR GO; GO:0015979; P:photosynthesis; IDA:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0006393; P:termination of mitochondrial transcription; IDA:TAIR.
DR Gene3D; 1.25.70.10; -; 2.
DR InterPro; IPR003690; MTERF.
DR InterPro; IPR038538; MTERF_sf.
DR PANTHER; PTHR13068; PTHR13068; 1.
DR Pfam; PF02536; mTERF; 2.
DR SMART; SM00733; Mterf; 8.
PE 1: Evidence at protein level;
KW Chloroplast; Plastid; Reference proteome; Transcription;
KW Transcription regulation; Transcription termination; Transit peptide.
FT TRANSIT 1..64
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 65..500
FT /note="Transcription termination factor MTERF8,
FT chloroplastic"
FT /id="PRO_0000436200"
FT CONFLICT 14
FT /note="F -> S (in Ref. 4; AAM65747)"
FT /evidence="ECO:0000305"
FT CONFLICT 76
FT /note="S -> N (in Ref. 4; AAM65747)"
FT /evidence="ECO:0000305"
FT CONFLICT 264
FT /note="D -> N (in Ref. 4; AAM65747)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 500 AA; 56350 MW; 6E0F8DD6ABE43862 CRC64;
MVILSLVSCS FSVFSPPISL RLHLPPVTSL CSHGTFPASS TFRSQLQPLL ISCLNHREPA
LTFRCSCLSS PIESGSQIES LFSLFRDIGF IEEETEMILA KNPDIKSTSL DKIGARVASL
QSLKINGFPL QGLIAKCPNL LTSEEFDLVI SFLVDELEGR LDPELVERLL SVVDTSILLS
FNQKVRLLLL HGIPKEKISH VLNKVYLNKL LYQKSVEDIE RLISFLEPFG GIGIIARRPV
ILNSDLDSQL IPRVDFIRNL SGEDDFATGT VLRRLPAILS YSVEHMNGQV EFLKSFAGLT
SEQVFKIVHV FPNVISTSKE RKLRPRIEFL KECGFDSPGM FKFLSKAPLI LALSENNLSH
KLGFLVKIGY KHRTKELAFA MGAVTRTSSD NMQRVIGLYL SYGLSFEDIL AMSTKHPQVL
QYNYTSLEEK LEYLIEYMGR EVEELLAFPA FLGYKLDSRI KHRYEEKLKS RGENMSLNKL
LTVSAERFSK AADNIEMICL
