MTEF9_ARATH
ID MTEF9_ARATH Reviewed; 496 AA.
AC Q9FM80;
DT 11-MAY-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 25-MAY-2022, entry version 118.
DE RecName: Full=Transcription termination factor MTERF9, chloroplastic {ECO:0000305};
DE AltName: Full=Mitochondrial transcription termination factor 9 {ECO:0000303|PubMed:23087700};
DE AltName: Full=Protein TWIRT1 {ECO:0000303|PubMed:21599977};
DE Flags: Precursor;
GN Name=MTERF9 {ECO:0000303|PubMed:23087700};
GN OrderedLocusNames=At5g55580 {ECO:0000312|Araport:AT5G55580};
GN ORFNames=MDF20.2 {ECO:0000312|EMBL:BAB09225.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9628582; DOI=10.1093/dnares/5.1.41;
RA Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence
RT features of the regions of 1,456,315 bp covered by nineteen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:41-54(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP DISRUPTION PHENOTYPE.
RX PubMed=21599977; DOI=10.1186/1471-2164-12-256;
RA Mokry M., Nijman I.J., van Dijken A., Benjamins R., Heidstra R.,
RA Scheres B., Cuppen E.;
RT "Identification of factors required for meristem function in Arabidopsis
RT using a novel next generation sequencing fast forward genetics approach.";
RL BMC Genomics 12:256-256(2011).
RN [5]
RP SUBCELLULAR LOCATION.
RX PubMed=21464319; DOI=10.1073/pnas.1103442108;
RA Babiychuk E., Vandepoele K., Wissing J., Garcia-Diaz M., De Rycke R.,
RA Akbari H., Joubes J., Beeckman T., Jaensch L., Frentzen M.,
RA Van Montagu M.C., Kushnir S.;
RT "Plastid gene expression and plant development require a plastidic protein
RT of the mitochondrial transcription termination factor family.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:6674-6679(2011).
RN [6]
RP GENE FAMILY.
RX PubMed=23087700; DOI=10.3389/fpls.2012.00233;
RA Kleine T.;
RT "Arabidopsis thaliana mTERF proteins: evolution and functional
RT classification.";
RL Front. Plant Sci. 3:233-233(2012).
RN [7]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=25393651; DOI=10.1111/ppl.12307;
RA Robles P., Micol J.L., Quesada V.;
RT "Mutations in the plant-conserved MTERF9 alter chloroplast gene expression,
RT development and tolerance to abiotic stress in Arabidopsis thaliana.";
RL Physiol. Plantarum 154:297-313(2015).
CC -!- FUNCTION: Transcription termination factor required for processing and
CC steady-state levels of plastid transcripts. May play a role in response
CC to abiotic stresses. {ECO:0000269|PubMed:25393651}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC {ECO:0000269|PubMed:21464319}.
CC -!- DISRUPTION PHENOTYPE: Variegated leaves, reduced growth and altered
CC structure of chloroplasts. Altered responses to sugars, abscisic acid
CC (ABA), salt and osmotic stresses during seedling establishment
CC (PubMed:25393651). Altered root and shoot meristem function resulting
CC in reduced organ growth (PubMed:21599977).
CC {ECO:0000269|PubMed:21599977, ECO:0000269|PubMed:25393651}.
CC -!- SIMILARITY: Belongs to the mTERF family. {ECO:0000305}.
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DR EMBL; AB009050; BAB09225.1; -; Genomic_DNA.
DR EMBL; CP002688; AED96652.1; -; Genomic_DNA.
DR EMBL; AY062691; AAL32769.1; -; mRNA.
DR EMBL; BT000141; AAN15460.1; -; mRNA.
DR RefSeq; NP_200369.1; NM_124940.4.
DR AlphaFoldDB; Q9FM80; -.
DR SMR; Q9FM80; -.
DR STRING; 3702.AT5G55580.1; -.
DR PaxDb; Q9FM80; -.
DR PRIDE; Q9FM80; -.
DR EnsemblPlants; AT5G55580.1; AT5G55580.1; AT5G55580.
DR GeneID; 835652; -.
DR Gramene; AT5G55580.1; AT5G55580.1; AT5G55580.
DR KEGG; ath:AT5G55580; -.
DR Araport; AT5G55580; -.
DR TAIR; locus:2162092; AT5G55580.
DR eggNOG; KOG1267; Eukaryota.
DR HOGENOM; CLU_032090_2_1_1; -.
DR InParanoid; Q9FM80; -.
DR OrthoDB; 714607at2759; -.
DR PhylomeDB; Q9FM80; -.
DR PRO; PR:Q9FM80; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FM80; baseline and differential.
DR GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR GO; GO:0003690; F:double-stranded DNA binding; IEA:InterPro.
DR GO; GO:1904821; P:chloroplast disassembly; IMP:TAIR.
DR GO; GO:0009658; P:chloroplast organization; IMP:TAIR.
DR GO; GO:0032502; P:developmental process; IBA:GO_Central.
DR GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEP:TAIR.
DR GO; GO:0009651; P:response to salt stress; IMP:TAIR.
DR GO; GO:0048364; P:root development; IMP:TAIR.
DR GO; GO:0048367; P:shoot system development; IMP:TAIR.
DR GO; GO:0010343; P:singlet oxygen-mediated programmed cell death; IMP:TAIR.
DR Gene3D; 1.25.70.10; -; 1.
DR InterPro; IPR003690; MTERF.
DR InterPro; IPR038538; MTERF_sf.
DR PANTHER; PTHR13068; PTHR13068; 1.
DR Pfam; PF02536; mTERF; 1.
DR SMART; SM00733; Mterf; 6.
PE 2: Evidence at transcript level;
KW Chloroplast; Plastid; Reference proteome; Transcription;
KW Transcription regulation; Transcription termination; Transit peptide.
FT TRANSIT 1..44
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 45..496
FT /note="Transcription termination factor MTERF9,
FT chloroplastic"
FT /id="PRO_0000436201"
FT REGION 57..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 102..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..90
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 496 AA; 57202 MW; 1DCEBCABFF9B8FA1 CRC64;
MAGFSLYCFK NPRILFTLPS ESPLFVLGSD KCSPATRRPS RKTRGFVVTY AHSNPKIINP
KKKSRYGQTL SPYDSDEDDD DDDDDDDDDW LLNDDFAEVT EYEKKKPKSH KQTIAKKSVK
KGIVKPEESE TDEDDLDLGI SPNATSEKKK ESWRLDGRGK MSSRKYVEKL YPRLAEEIDI
DPKCVPLLDY LSTFGLKESH FVQMYERHMP SLQINVFSAQ ERLDYLLSVG VKHRDIKRML
LRQPQILQYT VENNLKAHIS FLMGLGIPNS KIGQIVAATP SLFSYSVENS LRPTIRYLIE
EVGIKETDVG KVVQLSPQIL VQRLDITWNT RYMFLSKELG APRDSVVKMV KKHPQLLHYS
IDDGFLPRIN FLRSIGMCNS DILKVLTSLT QVLSLSLEDN LKPKYMYLVN ELNNEVHILT
KYPMYLSLSL DQRIRPRHRF LVELKKVRKG PFPLSSLVPN DESFCQQWAG TSVDTYLAFR
QRLLLKEFAN KYDKRG
