ID   MTFA_SALTY              Reviewed;         265 AA.
AC   Q8ZNS5;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Protein MtfA {ECO:0000255|HAMAP-Rule:MF_01593};
DE   AltName: Full=Mlc titration factor A {ECO:0000255|HAMAP-Rule:MF_01593};
GN   Name=mtfA {ECO:0000255|HAMAP-Rule:MF_01593}; OrderedLocusNames=STM2001;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Involved in the regulation of ptsG expression by binding and
CC       inactivating Mlc. {ECO:0000255|HAMAP-Rule:MF_01593}.
CC   -!- SUBUNIT: Interacts with Mlc. {ECO:0000255|HAMAP-Rule:MF_01593}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01593}.
CC   -!- SIMILARITY: Belongs to the MtfA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01593}.
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DR   EMBL; AE006468; AAL20910.1; -; Genomic_DNA.
DR   RefSeq; NP_460951.1; NC_003197.2.
DR   RefSeq; WP_000598920.1; NC_003197.2.
DR   AlphaFoldDB; Q8ZNS5; -.
DR   SMR; Q8ZNS5; -.
DR   STRING; 99287.STM2001; -.
DR   MEROPS; M90.001; -.
DR   PaxDb; Q8ZNS5; -.
DR   EnsemblBacteria; AAL20910; AAL20910; STM2001.
DR   GeneID; 1253522; -.
DR   KEGG; stm:STM2001; -.
DR   PATRIC; fig|99287.12.peg.2118; -.
DR   HOGENOM; CLU_063037_2_0_6; -.
DR   OMA; EHSGEAW; -.
DR   PhylomeDB; Q8ZNS5; -.
DR   BioCyc; SENT99287:STM2001-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0004177; F:aminopeptidase activity; IBA:GO_Central.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProt.
DR   GO; GO:0051090; P:regulation of DNA-binding transcription factor activity; IBA:GO_Central.
DR   CDD; cd20169; Peptidase_M90_mtfA; 1.
DR   Gene3D; 1.10.472.150; -; 1.
DR   Gene3D; 3.40.390.10; -; 1.
DR   HAMAP; MF_01593; MtfA; 1.
DR   InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR   InterPro; IPR010384; MtfA_fam.
DR   InterPro; IPR042252; MtfA_N.
DR   PANTHER; PTHR30164; PTHR30164; 1.
DR   Pfam; PF06167; Peptidase_M90; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..265
FT                   /note="Protein MtfA"
FT                   /id="PRO_0000316322"
SQ   SEQUENCE   265 AA;  30192 MW;  81C1BD758543CC3E CRC64;
     MIKWPWKAQE ITQNEDWPWD DALAIPLLVN LTAQEQARLI ALAERFLQQK RLVALQGFEL
     DSLKSARIAL IFCLPILELG IEWLDGFHEV LIYPAPFVVD DEWEDDIGLV HSQRVVQSGQ
     SWQQGPIILN WLDIQDSFDA SGFNLIIHEV AHKLDMRNGD RASGIPFIPL RDVAGWEHDL
     HAAMNNIQDE IDLVGESAAS IDAYAATDPA ECFAVLSEYF FSAPELFAPR FPALWQRFCQ
     FYRQDPSQRL RVSAAEGDYG EESEH