ID   MTFA_SERP5              Reviewed;         262 AA.
AC   A8GGH0;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Protein MtfA {ECO:0000255|HAMAP-Rule:MF_01593};
DE   AltName: Full=Mlc titration factor A {ECO:0000255|HAMAP-Rule:MF_01593};
GN   Name=mtfA {ECO:0000255|HAMAP-Rule:MF_01593}; OrderedLocusNames=Spro_3110;
OS   Serratia proteamaculans (strain 568).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Serratia.
OX   NCBI_TaxID=399741;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=568;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Taghavi S., Newman L.,
RA   Vangronsveld J., van der Lelie D., Richardson P.;
RT   "Complete sequence of chromosome of Serratia proteamaculans 568.";
RL   Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in the regulation of ptsG expression by binding and
CC       inactivating Mlc. {ECO:0000255|HAMAP-Rule:MF_01593}.
CC   -!- SUBUNIT: Interacts with Mlc. {ECO:0000255|HAMAP-Rule:MF_01593}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01593}.
CC   -!- SIMILARITY: Belongs to the MtfA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01593}.
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DR   EMBL; CP000826; ABV42210.1; -; Genomic_DNA.
DR   RefSeq; WP_012145830.1; NC_009832.1.
DR   AlphaFoldDB; A8GGH0; -.
DR   SMR; A8GGH0; -.
DR   STRING; 399741.Spro_3110; -.
DR   MEROPS; M90.001; -.
DR   EnsemblBacteria; ABV42210; ABV42210; Spro_3110.
DR   KEGG; spe:Spro_3110; -.
DR   eggNOG; COG3228; Bacteria.
DR   HOGENOM; CLU_063037_2_0_6; -.
DR   OMA; EHSGEAW; -.
DR   OrthoDB; 1806453at2; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProt.
DR   CDD; cd20169; Peptidase_M90_mtfA; 1.
DR   Gene3D; 1.10.472.150; -; 1.
DR   Gene3D; 3.40.390.10; -; 1.
DR   HAMAP; MF_01593; MtfA; 1.
DR   InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR   InterPro; IPR010384; MtfA_fam.
DR   InterPro; IPR042252; MtfA_N.
DR   PANTHER; PTHR30164; PTHR30164; 1.
DR   Pfam; PF06167; Peptidase_M90; 1.
PE   3: Inferred from homology;
KW   Cytoplasm.
FT   CHAIN           1..262
FT                   /note="Protein MtfA"
FT                   /id="PRO_1000185710"
SQ   SEQUENCE   262 AA;  29416 MW;  84E109D87ED084A2 CRC64;
     MIKWPWKTHQ PQAETLAQWQ DALAIPLLSP LDEREQQRLI VVAGQILQQK SIVPLQGLVL
     TSQMQARIAL LFALPVLELG AECLDGFNEI LLYPSPFVVE DEWQDDFGLV HSGPVVQSGQ
     SWEQGPIVLN WQDVQDSFDL SGFNLVIHEA VHKLDMRNGG SATGIPPIPL RDIAAWEHDL
     HAAMENLQDE IDMVGEEAAS MDAYAATDPA ECFAVLSEYF FSAPELLANR FPVMYQHFSR
     FYKQDPLARL QRLQAENSAE VP