MTFA_SHIDS
ID MTFA_SHIDS Reviewed; 265 AA.
AC Q32HG9;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-FEB-2008, sequence version 2.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=Protein MtfA {ECO:0000255|HAMAP-Rule:MF_01593};
DE AltName: Full=Mlc titration factor A {ECO:0000255|HAMAP-Rule:MF_01593};
GN Name=mtfA {ECO:0000255|HAMAP-Rule:MF_01593}; OrderedLocusNames=SDY_1072;
OS Shigella dysenteriae serotype 1 (strain Sd197).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=300267;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Sd197;
RX PubMed=16275786; DOI=10.1093/nar/gki954;
RA Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J.,
RA Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J.,
RA Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J.,
RA Jin Q.;
RT "Genome dynamics and diversity of Shigella species, the etiologic agents of
RT bacillary dysentery.";
RL Nucleic Acids Res. 33:6445-6458(2005).
CC -!- FUNCTION: Involved in the regulation of ptsG expression by binding and
CC inactivating Mlc. {ECO:0000255|HAMAP-Rule:MF_01593}.
CC -!- SUBUNIT: Interacts with Mlc. {ECO:0000255|HAMAP-Rule:MF_01593}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01593}.
CC -!- SIMILARITY: Belongs to the MtfA family. {ECO:0000255|HAMAP-
CC Rule:MF_01593}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABB61236.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; CP000034; ABB61236.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_005023745.1; NC_007606.1.
DR RefSeq; YP_402727.1; NC_007606.1.
DR AlphaFoldDB; Q32HG9; -.
DR SMR; Q32HG9; -.
DR STRING; 300267.SDY_1072; -.
DR MEROPS; M90.001; -.
DR EnsemblBacteria; ABB61236; ABB61236; SDY_1072.
DR KEGG; sdy:SDY_1072; -.
DR PATRIC; fig|300267.13.peg.1261; -.
DR HOGENOM; CLU_063037_0_1_6; -.
DR Proteomes; UP000002716; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProt.
DR CDD; cd20169; Peptidase_M90_mtfA; 1.
DR Gene3D; 1.10.472.150; -; 1.
DR Gene3D; 3.40.390.10; -; 1.
DR HAMAP; MF_01593; MtfA; 1.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR010384; MtfA_fam.
DR InterPro; IPR042252; MtfA_N.
DR PANTHER; PTHR30164; PTHR30164; 1.
DR Pfam; PF06167; Peptidase_M90; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome.
FT CHAIN 1..265
FT /note="Protein MtfA"
FT /id="PRO_0000316324"
SQ SEQUENCE 265 AA; 30221 MW; 3CAE3664FCECF8A7 CRC64;
MIKWPQKVQE SAHQTALPWQ EALSIPLLTC LTEQEQSKLV TLAERFLQQK RLVPLQGFEL
DSLRSCRIAL LFCLPVLELG LEWLDGFHEV LIYPAPFVVD DEWEDDIGLV HNQRIVQSGQ
SWQQGPIVLN WLDIQDSFDA SGFNLIIHEV AHKLDTRNGD RASGVPFIPL REVAGWEHDL
HAAMNNIQEE IELVGENAAS IDAYAASDPA ECFAVLSEYF FSAPELFAPR FPSLWQRFCQ
FYQQDPLQRL HHANDTDSFS ATNVH