ID   MTFP1_CAEBR             Reviewed;         162 AA.
AC   B6IJ52;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=Mitochondrial fission process protein 1;
DE   AltName: Full=Mitochondrial 18 kDa protein;
DE            Short=MTP18 {ECO:0000250|UniProtKB:Q8T3C8};
GN   ORFNames=CBG28141 {ECO:0000312|WormBase:CBG28141};
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1] {ECO:0000312|EMBL:CAS00032.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16 {ECO:0000312|EMBL:CAS00032.1};
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Involved in the mitochondrial division probably by regulating
CC       membrane fission. Loss-of-function leads to apoptosis (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000305};
CC       Multi-pass membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the MTFP1 family. {ECO:0000305}.
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DR   EMBL; HE600983; CAS00032.1; -; Genomic_DNA.
DR   AlphaFoldDB; B6IJ52; -.
DR   STRING; 6238.CBG28141; -.
DR   WormBase; CBG28141; CBP44102; WBGene00164982; -.
DR   eggNOG; KOG3945; Eukaryota.
DR   HOGENOM; CLU_053720_1_0_1; -.
DR   InParanoid; B6IJ52; -.
DR   OMA; DVFTWQM; -.
DR   Proteomes; UP000008549; Chromosome X.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0000266; P:mitochondrial fission; IBA:GO_Central.
DR   InterPro; IPR019560; Mitochondrial_18_kDa_protein.
DR   PANTHER; PTHR11001; PTHR11001; 1.
DR   Pfam; PF10558; MTP18; 2.
PE   3: Inferred from homology;
KW   Apoptosis; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..162
FT                   /note="Mitochondrial fission process protein 1"
FT                   /id="PRO_0000374063"
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        128..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   162 AA;  18259 MW;  811C8C2478DF26C5 CRC64;
     MSPVESSNVE KDIFRDTPVR FLGKRYANEV GEAFRSLVKP VVVKFSYVVA FGYVAADSVD
     KGFKESKKPH ANDTEKAKRV AIIAVDTVLW QTFASVLIPG FTINRFCFFT NMLLEKSTKL
     PTNLRKWTVT ALGLATIPFI VHPIDAFVED AMNKTARKVY NY