ID   MTFP1_CAEEL             Reviewed;         166 AA.
AC   Q8T3C8;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 2.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Mitochondrial fission process protein 1;
DE   AltName: Full=Mitochondrial 18 kDa protein;
DE            Short=MTP18 {ECO:0000250|UniProtKB:Q9UDX5};
GN   Name=mtp-18; ORFNames=T13C5.8;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Involved in the mitochondrial division probably by regulating
CC       membrane fission. Loss-of-function leads to apoptosis (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000305};
CC       Multi-pass membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the MTFP1 family. {ECO:0000305}.
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DR   EMBL; FO080546; CCD64559.1; -; Genomic_DNA.
DR   RefSeq; NP_001123181.1; NM_001129709.2.
DR   AlphaFoldDB; Q8T3C8; -.
DR   STRING; 6239.T13C5.8.1; -.
DR   EPD; Q8T3C8; -.
DR   PaxDb; Q8T3C8; -.
DR   PeptideAtlas; Q8T3C8; -.
DR   EnsemblMetazoa; T13C5.8.1; T13C5.8.1; WBGene00077690.
DR   GeneID; 6418865; -.
DR   KEGG; cel:CELE_T13C5.8; -.
DR   UCSC; T13C5.8.1; c. elegans.
DR   CTD; 6418865; -.
DR   WormBase; T13C5.8; CE42549; WBGene00077690; mtp-18.
DR   eggNOG; KOG3945; Eukaryota.
DR   GeneTree; ENSGT00390000004019; -.
DR   HOGENOM; CLU_053720_1_0_1; -.
DR   InParanoid; Q8T3C8; -.
DR   OMA; DVFTWQM; -.
DR   OrthoDB; 1477184at2759; -.
DR   PhylomeDB; Q8T3C8; -.
DR   PRO; PR:Q8T3C8; -.
DR   Proteomes; UP000001940; Chromosome X.
DR   Bgee; WBGene00077690; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0000266; P:mitochondrial fission; IBA:GO_Central.
DR   InterPro; IPR019560; Mitochondrial_18_kDa_protein.
DR   PANTHER; PTHR11001; PTHR11001; 1.
DR   Pfam; PF10558; MTP18; 2.
PE   3: Inferred from homology;
KW   Apoptosis; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..166
FT                   /note="Mitochondrial fission process protein 1"
FT                   /id="PRO_0000374064"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        125..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   166 AA;  18778 MW;  39F11EABDA6493B3 CRC64;
     MTPVEEIIKK DIFRETPLRY LGYANEVGEA FRSLVKPVVV KFSYVVAFGY VAADSIDKGL
     QEYIKTHSTS TEKTKKVAIA AVDTVLWQTF ASVLIPGFTI NRFCFFSNLL LQKSTKLPTN
     MRKWTVTCLG LATIPFIVHP IDSFVEEAMD KTARKIYNEP TISNKE