ID   MTFR1_PONAB             Reviewed;         333 AA.
AC   Q5RFN3;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Mitochondrial fission regulator 1;
DE   Flags: Precursor;
GN   Name=MTFR1;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in mitochondrial aerobic respiration. May
CC       also regulate mitochondrial organization and fission (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}. Note=May be
CC       associated with the inner and the outer mitochondrial membrane.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MTFR1 family. {ECO:0000305}.
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DR   EMBL; CR857120; CAH89424.1; -; mRNA.
DR   RefSeq; NP_001124603.1; NM_001131131.2.
DR   AlphaFoldDB; Q5RFN3; -.
DR   SMR; Q5RFN3; -.
DR   STRING; 9601.ENSPPYP00000020897; -.
DR   Ensembl; ENSPPYT00000021731; ENSPPYP00000020897; ENSPPYG00000018631.
DR   GeneID; 100171440; -.
DR   KEGG; pon:100171440; -.
DR   CTD; 9650; -.
DR   eggNOG; ENOG502QSSN; Eukaryota.
DR   GeneTree; ENSGT00950000183215; -.
DR   HOGENOM; CLU_059135_0_0_1; -.
DR   InParanoid; Q5RFN3; -.
DR   OMA; KKPEIPN; -.
DR   OrthoDB; 1485791at2759; -.
DR   TreeFam; TF331404; -.
DR   Proteomes; UP000001595; Chromosome 8.
DR   GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR   GO; GO:0009060; P:aerobic respiration; ISS:UniProtKB.
DR   GO; GO:0000266; P:mitochondrial fission; ISS:UniProtKB.
DR   GO; GO:0007005; P:mitochondrion organization; ISS:UniProtKB.
DR   InterPro; IPR007972; Mtfr1.
DR   PANTHER; PTHR14215; PTHR14215; 1.
DR   Pfam; PF05308; Mito_fiss_reg; 1.
PE   2: Evidence at transcript level;
KW   Mitochondrion; Phosphoprotein; Reference proteome; Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..333
FT                   /note="Mitochondrial fission regulator 1"
FT                   /id="PRO_0000096624"
FT   REGION          286..315
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        286..303
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         119
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q15390"
SQ   SEQUENCE   333 AA;  37018 MW;  FF2DF439BD954D0E CRC64;
     MLGWIKRLIR MVFQQVGVSM QSVLWSRKPY GSSRSIVRKI GTNLSLIQCP RVQFQINSHA
     TEWSPSHPGE DAVASFADVG WVAKEEGECS ARLRTEVRSR PPLQDDLLFF EKAPSRQISL
     PDFSQEEPQL KTPALANEEA LQKICALENE LAALRAQIAK IVTQQEQQNL TAGDLDSTTF
     GTIPPHPLPP PPPPPPPPLG LHQSISAVDL IKERREKRAN AGKTLVKNSP KKPEMPNMLE
     ILKDMNSVKL RSVKRSEQDV KPKPVDATDP AALIAEALKK KFAYRYRSDS QDEVEKGVPK
     SESEATSERV LFGPHMLKPT GKMKALIENV SDS