ID   MTG1_ICTPU              Reviewed;         320 AA.
AC   E3TDS3;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   11-JAN-2011, sequence version 1.
DT   03-AUG-2022, entry version 35.
DE   RecName: Full=Mitochondrial ribosome-associated GTPase 1;
DE   AltName: Full=Mitochondrial GTPase 1 {ECO:0000312|EMBL:ADO28459.1};
DE   Flags: Precursor;
GN   Name=mtg1 {ECO:0000312|EMBL:ADO28459.1};
OS   Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC   Ictaluridae; Ictalurus.
OX   NCBI_TaxID=7998;
RN   [1] {ECO:0000312|EMBL:ADO28459.1}
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=20634964; DOI=10.1371/journal.pone.0011546;
RA   Chen F., Lee Y., Jiang Y., Wang S., Peatman E., Abernathy J., Liu H.,
RA   Liu S., Kucuktas H., Ke C., Liu Z.;
RT   "Identification and characterization of full-length cDNAs in channel
RT   catfish (Ictalurus punctatus) and blue catfish (Ictalurus furcatus).";
RL   PLoS ONE 5:E11546-E11546(2010).
CC   -!- FUNCTION: Plays a role in the regulation of the mitochondrial ribosome
CC       assembly and of translational activity (By similarity). Displays
CC       mitochondrial GTPase activity (By similarity).
CC       {ECO:0000250|UniProtKB:Q9BT17}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:Q9BT17}; Peripheral membrane protein
CC       {ECO:0000250|UniProtKB:Q9BT17}; Matrix side
CC       {ECO:0000250|UniProtKB:Q9BT17}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU01058}.
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DR   EMBL; GU588503; ADO28459.1; -; mRNA.
DR   RefSeq; NP_001187294.1; NM_001200365.1.
DR   AlphaFoldDB; E3TDS3; -.
DR   SMR; E3TDS3; -.
DR   STRING; 7998.ENSIPUP00000026411; -.
DR   GeneID; 100528095; -.
DR   KEGG; ipu:100528095; -.
DR   CTD; 92170; -.
DR   OrthoDB; 583045at2759; -.
DR   Proteomes; UP000221080; Chromosome 3.
DR   GO; GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.
DR   GO; GO:0005759; C:mitochondrial matrix; ISS:UniProtKB.
DR   GO; GO:0005761; C:mitochondrial ribosome; ISS:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1580.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR030378; G_CP_dom.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR023179; GTP-bd_ortho_bundle_sf.
DR   InterPro; IPR016478; GTPase_MTG1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   PIRSF; PIRSF006230; MG442; 1.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51721; G_CP; 1.
PE   2: Evidence at transcript level;
KW   GTP-binding; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   Nucleotide-binding; Transit peptide; Translation regulation.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BT17, ECO:0000255"
FT   CHAIN           ?..320
FT                   /note="Mitochondrial ribosome-associated GTPase 1"
FT                   /id="PRO_0000409873"
FT   DOMAIN          37..209
FT                   /note="CP-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01058"
FT   BINDING         81..84
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:O31743"
FT   BINDING         153..158
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:O31743"
FT   BINDING         205
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:O31743"
SQ   SEQUENCE   320 AA;  36016 MW;  ADA314AA0CC25338 CRC64;
     MRISHTLLNA SSKFRTVFDF GERQVAHWFP GHMAKGLKQM RASPRKVDCV IEIHDARIPF
     SGRNPLFQEN LDVRPHLLIL NKMDLADTSD KMSILKQLER DGVKNVLLTD CLKQRDTSVK
     KIIPLVTDLI ENAPRFHREE NRSYCLMVIG VPNVGKSSLI NAIRRTNLKK GKASRVGGEP
     GITKAVLTKI QVCERPVIHL LDTPGVLPPK IENIETGMKL ALCGTILDHL VGEDIIADYL
     LFSLNRPQRF GYVERYDLET PSDDIQHVLK CIAVKLGKTQ RVKAITGVGD ITVRMPNYTA
     AAYDFIRAFR KGELGKVMLD