ID   MTG1_XENTR              Reviewed;         311 AA.
AC   A9JTX2;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Mitochondrial ribosome-associated GTPase 1;
DE   AltName: Full=Mitochondrial GTPase 1 {ECO:0000250|UniProtKB:Q9BT17};
DE   Flags: Precursor;
GN   Name=mtg1 {ECO:0000312|Xenbase:XB-GENE-957647};
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1] {ECO:0000312|EMBL:AAI55523.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=N6 {ECO:0000312|EMBL:AAI55523.1};
RC   TISSUE=Ovary {ECO:0000312|EMBL:AAI55523.1};
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in the regulation of the mitochondrial ribosome
CC       assembly and of translational activity (By similarity). Displays
CC       mitochondrial GTPase activity (By similarity).
CC       {ECO:0000250|UniProtKB:Q9BT17}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:Q9BT17}; Peripheral membrane protein
CC       {ECO:0000250|UniProtKB:Q9BT17}; Matrix side
CC       {ECO:0000250|UniProtKB:Q9BT17}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU01058}.
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DR   EMBL; BC155522; AAI55523.1; -; mRNA.
DR   RefSeq; NP_001106634.1; NM_001113163.2.
DR   RefSeq; XP_012821402.1; XM_012965948.2.
DR   RefSeq; XP_012821403.1; XM_012965949.2.
DR   RefSeq; XP_017950730.1; XM_018095241.1.
DR   AlphaFoldDB; A9JTX2; -.
DR   SMR; A9JTX2; -.
DR   PaxDb; A9JTX2; -.
DR   GeneID; 100127874; -.
DR   KEGG; xtr:100127874; -.
DR   CTD; 92170; -.
DR   Xenbase; XB-GENE-957647; mtg1.
DR   eggNOG; KOG2485; Eukaryota.
DR   HOGENOM; CLU_011106_0_2_1; -.
DR   InParanoid; A9JTX2; -.
DR   OrthoDB; 583045at2759; -.
DR   Proteomes; UP000008143; Chromosome 7.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000022149; Expressed in heart and 10 other tissues.
DR   GO; GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.
DR   GO; GO:0005759; C:mitochondrial matrix; ISS:UniProtKB.
DR   GO; GO:0005761; C:mitochondrial ribosome; ISS:UniProtKB.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR   GO; GO:0032543; P:mitochondrial translation; IBA:GO_Central.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0006412; P:translation; IBA:GO_Central.
DR   Gene3D; 1.10.1580.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR030378; G_CP_dom.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR023179; GTP-bd_ortho_bundle_sf.
DR   InterPro; IPR016478; GTPase_MTG1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   PIRSF; PIRSF006230; MG442; 1.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51721; G_CP; 1.
PE   2: Evidence at transcript level;
KW   GTP-binding; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   Nucleotide-binding; Reference proteome; Transit peptide;
KW   Translation regulation.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BT17, ECO:0000255"
FT   CHAIN           ?..311
FT                   /note="Mitochondrial ribosome-associated GTPase 1"
FT                   /id="PRO_0000409874"
FT   DOMAIN          27..200
FT                   /note="CP-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01058"
FT   BINDING         74..77
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:O31743"
FT   BINDING         144..149
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:O31743"
FT   BINDING         196
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:O31743"
SQ   SEQUENCE   311 AA;  34977 MW;  52380AA16EF8FDF8 CRC64;
     MRLSWLLRKS FDFGEREVAH WFPGHMAKGL KQMKTKLKNL DCIVEVHDAR IPLSGRNPIF
     QDSLGMKPHL LILNKMDLAD LTQKKRILAQ LKQQGVGNVI FTDCVKDQNI KHVVPVISEL
     VGCSQRFHRE ENTETCIMVI GVPNVGKSSL INALRRMHLR KGKASRVGAE PGITRSVLTK
     IQVSESPLIF LFDTPGVLSP RIESVETGMK LALCGTILDH LVGEDIMADY LLYILNQQMQ
     HRYVEHYGLE KPCADIETLL KRIALKLGKT QKVKAITGVG DVNITVPNYN AAAYDFIRTF
     RRGQLGVVML D