ID   MTM9L_BOVIN             Reviewed;         543 AA.
AC   Q2KJ24;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Myotubularin-related protein 9-like {ECO:0000305};
DE   AltName: Full=Inactive phosphatidylinositol 3-phosphatase 9-like {ECO:0000305};
GN   Name=MTMR9L {ECO:0000305};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Ascending colon;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable pseudophosphatase. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC       receptor class myotubularin subfamily. {ECO:0000305}.
CC   -!- CAUTION: Although it belongs to the non-receptor class myotubularin
CC       subfamily, lacks the conserved active site cysteine residue at position
CC       337 in the dsPTPase catalytic loop, suggesting that it has no
CC       phosphatase activity. {ECO:0000305}.
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DR   EMBL; BC105556; AAI05557.1; -; mRNA.
DR   RefSeq; NP_001039721.1; NM_001046256.1.
DR   RefSeq; XP_015315000.1; XM_015459514.1.
DR   AlphaFoldDB; Q2KJ24; -.
DR   SMR; Q2KJ24; -.
DR   STRING; 9913.ENSBTAP00000019137; -.
DR   PaxDb; Q2KJ24; -.
DR   PRIDE; Q2KJ24; -.
DR   Ensembl; ENSBTAT00000019137; ENSBTAP00000019137; ENSBTAG00000014390.
DR   GeneID; 521746; -.
DR   KEGG; bta:521746; -.
DR   CTD; 66036; -.
DR   VEuPathDB; HostDB:ENSBTAG00000014390; -.
DR   eggNOG; KOG1089; Eukaryota.
DR   GeneTree; ENSGT00940000163547; -.
DR   HOGENOM; CLU_001839_3_1_1; -.
DR   InParanoid; Q2KJ24; -.
DR   OMA; CRWLAHV; -.
DR   OrthoDB; 824298at2759; -.
DR   TreeFam; TF315197; -.
DR   Proteomes; UP000009136; Chromosome 2.
DR   Bgee; ENSBTAG00000014390; Expressed in saliva-secreting gland and 103 other tissues.
DR   GO; GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IBA:GO_Central.
DR   GO; GO:0010507; P:negative regulation of autophagy; IBA:GO_Central.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IBA:GO_Central.
DR   Gene3D; 2.30.29.30; -; 1.
DR   InterPro; IPR010569; Myotubularin-like_Pase_dom.
DR   InterPro; IPR030564; Myotubularin_fam.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   PANTHER; PTHR10807; PTHR10807; 1.
DR   Pfam; PF06602; Myotub-related; 1.
DR   SUPFAM; SSF52799; SSF52799; 1.
DR   PROSITE; PS51339; PPASE_MYOTUBULARIN; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..543
FT                   /note="Myotubularin-related protein 9-like"
FT                   /id="PRO_0000240348"
FT   DOMAIN          124..502
FT                   /note="Myotubularin phosphatase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00669"
SQ   SEQUENCE   543 AA;  60786 MW;  CA75ABADD6843966 CRC64;
     MEFAEMIRTG QAQAELLRGP EEPPLRGTLC ITGHHLLLSP GPQATPDLWL LLLRNVDSIE
     KRVAGDSGTI TLRCKDLRVL QLDIEGVEAT LDIARSIEAL SSLESVITSF PFFYRPKGLR
     LGDAWHFHPP ECYYKRVARE TNAWRLSEAN EDFSLCPSYP RAVIVPRAVD DSAVARSARF
     RQGGRFPVLS YYHAPSGTVL LRAGQPLTGP QKRRCSEDEE LLRAVLAGAR PGARGFIVDT
     RSPQAAKQAR MTGGGTEAKA AYPGWKRLHR PLERGRPLQE SFVRLVEACG DLEQSMDRWL
     NRLESCRWLS HVKETLSTAC LAAQSMEQEG ACILVHGAEG TDSTLLITSL AQLILDPLSR
     TMAGFQELIE REWVQAGHPF QLRCAHSAFS HARPKHEAPT FLLFLDCVWQ LGRQFPLSLE
     FGEGMLLALF DHAYASPFGT FLCNNEKERC LCEVRTRTHS LWSGLSQPKE QRKLRNPLYV
     PNPLAIWPSA EPQSLRLWQG LFLRGTRPPE PSEVAWEKVW QIVTDQEKTE GSQPTDSASE
     PGP