ID   MTR2_CANAX              Reviewed;         181 AA.
AC   P84148;
DT   01-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=mRNA transport regulator MTR2;
GN   Name=MTR2;
OS   Candida albicans (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=5476;
RN   [1]
RP   X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS) IN COMPLEX WITH MEX67.
RX   PubMed=14504280; DOI=10.1074/jbc.m308275200;
RA   Senay C., Ferrari P., Rocher C., Rieger K.J., Winter J., Platel D.,
RA   Bourne Y.;
RT   "The Mtr2-Mex67 NTF2-like domain complex. Structural insights into a dual
RT   role of Mtr2 for yeast nuclear export.";
RL   J. Biol. Chem. 278:48395-48403(2003).
CC   -!- FUNCTION: Affects mRNA transport from the nucleus to the cytoplasm.
CC   -!- SUBUNIT: Interacts with MEX67. {ECO:0000269|PubMed:14504280}.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
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DR   PDB; 1Q40; X-ray; 1.95 A; A/C=1-181.
DR   PDB; 1Q42; X-ray; 1.75 A; A=1-181.
DR   PDBsum; 1Q40; -.
DR   PDBsum; 1Q42; -.
DR   AlphaFoldDB; P84148; -.
DR   SMR; P84148; -.
DR   VEuPathDB; FungiDB:C2_10640C_A; -.
DR   VEuPathDB; FungiDB:CAWG_06126; -.
DR   EvolutionaryTrace; P84148; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR019488; Nucl_pore_RNA_shuttling_Mtr2.
DR   Pfam; PF10429; Mtr2; 1.
DR   SUPFAM; SSF54427; SSF54427; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Nucleus; Transport.
FT   CHAIN           1..181
FT                   /note="mRNA transport regulator MTR2"
FT                   /id="PRO_0000096633"
FT   HELIX           5..7
FT                   /evidence="ECO:0007829|PDB:1Q42"
FT   HELIX           9..20
FT                   /evidence="ECO:0007829|PDB:1Q42"
FT   HELIX           35..39
FT                   /evidence="ECO:0007829|PDB:1Q42"
FT   TURN            40..45
FT                   /evidence="ECO:0007829|PDB:1Q42"
FT   STRAND          46..54
FT                   /evidence="ECO:0007829|PDB:1Q42"
FT   STRAND          63..65
FT                   /evidence="ECO:0007829|PDB:1Q40"
FT   HELIX           67..76
FT                   /evidence="ECO:0007829|PDB:1Q42"
FT   STRAND          81..93
FT                   /evidence="ECO:0007829|PDB:1Q42"
FT   TURN            94..97
FT                   /evidence="ECO:0007829|PDB:1Q42"
FT   STRAND          98..110
FT                   /evidence="ECO:0007829|PDB:1Q42"
FT   STRAND          112..114
FT                   /evidence="ECO:0007829|PDB:1Q40"
FT   STRAND          123..125
FT                   /evidence="ECO:0007829|PDB:1Q40"
FT   STRAND          144..154
FT                   /evidence="ECO:0007829|PDB:1Q42"
FT   STRAND          163..172
FT                   /evidence="ECO:0007829|PDB:1Q42"
SQ   SEQUENCE   181 AA;  20494 MW;  5CCFB6DC8A504B5E CRC64;
     MNQDPTQQLE PFLKRFLASL DLLYTQPTSQ PFPNVESYAT QLGSNLKRSS AIIVNGQPII
     PSPQEDCKLQ FQKKWLQTPL SSHQLTSYDG HLIPGTGTFV VHFSAKVRFD QSGRNRLGES
     ADLFQENNSI VSKTNQRPIW GSWFGVDVNL VVDENVMQDG EIINSMDYRF TYVPNDSIIK
     V