MTRB_ALKHC
ID MTRB_ALKHC Reviewed; 76 AA.
AC Q9KCC6;
DT 25-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 107.
DE RecName: Full=Transcription attenuation protein MtrB;
DE AltName: Full=Trp RNA-binding attenuation protein;
DE Short=TRAP;
DE AltName: Full=Tryptophan RNA-binding attenuator protein;
GN Name=mtrB; OrderedLocusNames=BH1647;
OS Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344
OS / JCM 9153 / C-125) (Bacillus halodurans).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalobacillus.
OX NCBI_TaxID=272558;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125;
RX PubMed=11058132; DOI=10.1093/nar/28.21.4317;
RA Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F.,
RA Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.;
RT "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans
RT and genomic sequence comparison with Bacillus subtilis.";
RL Nucleic Acids Res. 28:4317-4331(2000).
CC -!- FUNCTION: Required for transcription attenuation control in the Trp
CC operon. This trans-acting factor seems to recognize a 10 bases
CC nucleotide sequence in the Trp leader transcript causing transcription
CC termination. Binds the leader RNA only in presence of L-tryptophan (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Oligomer of 11 identical subunits arranged in doughnut-like
CC structure. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MtrB family. {ECO:0000305}.
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DR EMBL; BA000004; BAB05366.1; -; Genomic_DNA.
DR PIR; G83855; G83855.
DR RefSeq; WP_010897809.1; NC_002570.2.
DR PDB; 3ZZL; X-ray; 1.67 A; A/B/C=7-76.
DR PDBsum; 3ZZL; -.
DR AlphaFoldDB; Q9KCC6; -.
DR SMR; Q9KCC6; -.
DR STRING; 272558.10174264; -.
DR EnsemblBacteria; BAB05366; BAB05366; BAB05366.
DR KEGG; bha:BH1647; -.
DR eggNOG; ENOG5032Z9Y; Bacteria.
DR HOGENOM; CLU_180875_0_0_9; -.
DR OMA; KDTKFHH; -.
DR OrthoDB; 1974796at2; -.
DR Proteomes; UP000001258; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription, termination; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR Gene3D; 2.60.40.50; -; 1.
DR HAMAP; MF_00798; Trp_attenuator; 1.
DR InterPro; IPR000824; MtrB.
DR InterPro; IPR016031; Trp_RNA-bd_attenuator-like_dom.
DR InterPro; IPR023558; Trp_RNA-bd_attenuator_dom.
DR Pfam; PF02081; TrpBP; 1.
DR PRINTS; PR00687; TRPRNAAP.
DR SUPFAM; SSF51219; SSF51219; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; RNA-binding; Transcription;
KW Transcription regulation.
FT CHAIN 1..76
FT /note="Transcription attenuation protein MtrB"
FT /id="PRO_0000206025"
FT STRAND 9..17
FT /evidence="ECO:0007829|PDB:3ZZL"
FT STRAND 19..25
FT /evidence="ECO:0007829|PDB:3ZZL"
FT STRAND 32..38
FT /evidence="ECO:0007829|PDB:3ZZL"
FT STRAND 43..47
FT /evidence="ECO:0007829|PDB:3ZZL"
FT STRAND 50..65
FT /evidence="ECO:0007829|PDB:3ZZL"
FT STRAND 68..71
FT /evidence="ECO:0007829|PDB:3ZZL"
SQ SEQUENCE 76 AA; 8493 MW; B9FEB4A0CCDF9AB8 CRC64;
MNVGDNSNFF VIKAKENGVN VFGMTRGTDT RFHHSEKLDK GEVMIAQFTE HTSAVKIRGK
AIIQTSYGTL DTEKDE
