MTRB_BACPU
ID MTRB_BACPU Reviewed; 76 AA.
AC P48064;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 25-MAY-2022, entry version 85.
DE RecName: Full=Transcription attenuation protein MtrB;
DE AltName: Full=Trp RNA-binding attenuation protein;
DE Short=TRAP;
DE AltName: Full=Tryptophan RNA-binding attenuator protein;
GN Name=mtrB;
OS Bacillus pumilus (Bacillus mesentericus).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=1408;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=7836324; DOI=10.1128/jb.177.3.839-842.1995;
RA Hoffman R.J., Gollnick P.;
RT "The mtrB gene of Bacillus pumilus encodes a protein with sequence and
RT functional homology to the trp RNA-binding attenuation protein (TRAP) of
RT Bacillus subtilis.";
RL J. Bacteriol. 177:839-842(1995).
CC -!- FUNCTION: Required for transcription attenuation control in the Trp
CC operon. This trans-acting factor seems to recognize a 10 bases
CC nucleotide sequence in the Trp leader transcript causing transcription
CC termination. Binds the leader RNA only in presence of L-tryptophan.
CC -!- SUBUNIT: Oligomer of 11 identical subunits arranged in doughnut-like
CC structure. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MtrB family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; L37879; AAA67544.1; -; Genomic_DNA.
DR PIR; I39905; I39905.
DR RefSeq; WP_008344541.1; NZ_NKHG01000074.1.
DR AlphaFoldDB; P48064; -.
DR SMR; P48064; -.
DR GeneID; 61770023; -.
DR GeneID; 66363592; -.
DR OrthoDB; 1974796at2; -.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription, termination; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR Gene3D; 2.60.40.50; -; 1.
DR HAMAP; MF_00798; Trp_attenuator; 1.
DR InterPro; IPR000824; MtrB.
DR InterPro; IPR016031; Trp_RNA-bd_attenuator-like_dom.
DR InterPro; IPR023558; Trp_RNA-bd_attenuator_dom.
DR Pfam; PF02081; TrpBP; 1.
DR PRINTS; PR00687; TRPRNAAP.
DR SUPFAM; SSF51219; SSF51219; 1.
PE 3: Inferred from homology;
KW RNA-binding; Transcription; Transcription regulation.
FT CHAIN 1..76
FT /note="Transcription attenuation protein MtrB"
FT /id="PRO_0000206026"
SQ SEQUENCE 76 AA; 8301 MW; 22184B2351DA151D CRC64;
MSENKASDFV VIKAIDNGVN VIGLTRGSDT RFHHSEKLDK GEVIIAQFTE HTSAIKVRGD
AVIQTSFGEI QSEAKK