MTRB_GEOSW
ID MTRB_GEOSW Reviewed; 74 AA.
AC C5D3E7;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 62.
DE RecName: Full=Transcription attenuation protein MtrB {ECO:0000255|HAMAP-Rule:MF_00798};
DE AltName: Full=Trp RNA-binding attenuation protein {ECO:0000255|HAMAP-Rule:MF_00798};
DE Short=TRAP {ECO:0000255|HAMAP-Rule:MF_00798};
DE AltName: Full=Tryptophan RNA-binding attenuator protein {ECO:0000255|HAMAP-Rule:MF_00798};
GN Name=mtrB {ECO:0000255|HAMAP-Rule:MF_00798}; OrderedLocusNames=GWCH70_2152;
OS Geobacillus sp. (strain WCH70).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus;
OC unclassified Geobacillus.
OX NCBI_TaxID=471223;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WCH70;
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA Brumm P., Mead D.A., Richardson P.;
RT "Complete sequence of chromosome of Geopacillus sp. WCH70.";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for transcription attenuation control in the Trp
CC operon. This trans-acting factor seems to recognize a 10 bases
CC nucleotide sequence in the Trp leader transcript causing transcription
CC termination. Binds the leader RNA only in presence of L-tryptophan.
CC {ECO:0000255|HAMAP-Rule:MF_00798}.
CC -!- SUBUNIT: Oligomer of 11 identical subunits arranged in doughnut-like
CC structure. {ECO:0000255|HAMAP-Rule:MF_00798}.
CC -!- SIMILARITY: Belongs to the MtrB family. {ECO:0000255|HAMAP-
CC Rule:MF_00798}.
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DR EMBL; CP001638; ACS24862.1; -; Genomic_DNA.
DR RefSeq; WP_015864287.1; NC_012793.1.
DR AlphaFoldDB; C5D3E7; -.
DR SMR; C5D3E7; -.
DR STRING; 471223.GWCH70_2152; -.
DR EnsemblBacteria; ACS24862; ACS24862; GWCH70_2152.
DR KEGG; gwc:GWCH70_2152; -.
DR eggNOG; ENOG5032Z9Y; Bacteria.
DR HOGENOM; CLU_180875_0_0_9; -.
DR OMA; KDTKFHH; -.
DR OrthoDB; 1974796at2; -.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription, termination; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR Gene3D; 2.60.40.50; -; 1.
DR HAMAP; MF_00798; Trp_attenuator; 1.
DR InterPro; IPR000824; MtrB.
DR InterPro; IPR016031; Trp_RNA-bd_attenuator-like_dom.
DR InterPro; IPR023558; Trp_RNA-bd_attenuator_dom.
DR Pfam; PF02081; TrpBP; 1.
DR PRINTS; PR00687; TRPRNAAP.
DR SUPFAM; SSF51219; SSF51219; 1.
PE 3: Inferred from homology;
KW RNA-binding; Transcription; Transcription regulation.
FT CHAIN 1..74
FT /note="Transcription attenuation protein MtrB"
FT /id="PRO_1000212968"
SQ SEQUENCE 74 AA; 8265 MW; 4E52A2A6911CA1D4 CRC64;
MNINSDYIVI KALEDGVNVI GLTRGADTRF HHSEKLDKGE VLIAQFTEHT SAIKVRGKAY
IQTRHGEIES EGKK