ID   MTRB_META3              Reviewed;         108 AA.
AC   A6UWH6;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Tetrahydromethanopterin S-methyltransferase subunit B {ECO:0000255|HAMAP-Rule:MF_01094};
DE            EC=2.1.1.86 {ECO:0000255|HAMAP-Rule:MF_01094};
DE   AltName: Full=N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit B {ECO:0000255|HAMAP-Rule:MF_01094};
GN   Name=mtrB {ECO:0000255|HAMAP-Rule:MF_01094}; OrderedLocusNames=Maeo_1272;
OS   Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 /
OS   Nankai-3).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanococcaceae; Methanococcus.
OX   NCBI_TaxID=419665;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A.,
RA   Sieprawska-Lupa M., Whitman W.B., Richardson P.;
RT   "Complete sequence of Methanococcus aeolicus Nankai-3.";
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of a complex that catalyzes the formation of methyl-
CC       coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-
CC       tetrahydromethanopterin. This is an energy-conserving, sodium-ion
CC       translocating step. {ECO:0000255|HAMAP-Rule:MF_01094}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme M + 2
CC         Na(+)(in) = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M + 2
CC         Na(+)(out); Xref=Rhea:RHEA:53492, ChEBI:CHEBI:29101,
CC         ChEBI:CHEBI:58103, ChEBI:CHEBI:58116, ChEBI:CHEBI:58286,
CC         ChEBI:CHEBI:58319; EC=2.1.1.86; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_01094};
CC   -!- PATHWAY: One-carbon metabolism; methanogenesis from CO(2); methyl-
CC       coenzyme M from 5,10-methylene-5,6,7,8-tetrahydromethanopterin: step
CC       2/2. {ECO:0000255|HAMAP-Rule:MF_01094}.
CC   -!- SUBUNIT: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD,
CC       MtrE, MtrF, MtrG and MtrH. {ECO:0000255|HAMAP-Rule:MF_01094}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01094};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01094}.
CC   -!- SIMILARITY: Belongs to the MtrB family. {ECO:0000255|HAMAP-
CC       Rule:MF_01094}.
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DR   EMBL; CP000743; ABR56848.1; -; Genomic_DNA.
DR   RefSeq; WP_011973980.1; NC_009635.1.
DR   AlphaFoldDB; A6UWH6; -.
DR   STRING; 419665.Maeo_1272; -.
DR   EnsemblBacteria; ABR56848; ABR56848; Maeo_1272.
DR   GeneID; 5326678; -.
DR   KEGG; mae:Maeo_1272; -.
DR   eggNOG; arCOG04867; Archaea.
DR   HOGENOM; CLU_171544_0_0_2; -.
DR   OMA; TNMVYGF; -.
DR   OrthoDB; 114178at2157; -.
DR   UniPathway; UPA00640; UER00698.
DR   Proteomes; UP000001106; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030269; F:tetrahydromethanopterin S-methyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019386; P:methanogenesis, from carbon dioxide; IEA:UniProtKB-UniPathway.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01094; MtrB; 1.
DR   InterPro; IPR008690; MtrB_MeTrfase.
DR   Pfam; PF05440; MtrB; 1.
DR   PIRSF; PIRSF005518; MtrB; 1.
DR   TIGRFAMs; TIGR04166; methano_MtrB; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Methanogenesis; Methyltransferase;
KW   One-carbon metabolism; Reference proteome; Transferase; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..108
FT                   /note="Tetrahydromethanopterin S-methyltransferase subunit
FT                   B"
FT                   /id="PRO_1000064934"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01094"
SQ   SEQUENCE   108 AA;  11928 MW;  DCCE41B2840F1BEF CRC64;
     MELVKICPEI GIVMDVDTGI VAEMRKDILV VDLNPIKEEI NKLETLSKAF ENSLDPRSAP
     LKAYDGRDNI YSVGGLFQSA FFGFWISLSI LTLGLILVIG LYPKLIGL