ID   MTRB_METM7              Reviewed;         108 AA.
AC   A6VHF1;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Tetrahydromethanopterin S-methyltransferase subunit B {ECO:0000255|HAMAP-Rule:MF_01094};
DE            EC=2.1.1.86 {ECO:0000255|HAMAP-Rule:MF_01094};
DE   AltName: Full=N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit B {ECO:0000255|HAMAP-Rule:MF_01094};
GN   Name=mtrB {ECO:0000255|HAMAP-Rule:MF_01094}; OrderedLocusNames=MmarC7_0810;
OS   Methanococcus maripaludis (strain C7 / ATCC BAA-1331).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanococcaceae; Methanococcus.
OX   NCBI_TaxID=426368;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C7 / ATCC BAA-1331;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Clum A., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Anderson I., Sieprawska-Lupa M., Whitman W.B., Richardson P.;
RT   "Complete sequence of Methanococcus maripaludis C7.";
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of a complex that catalyzes the formation of methyl-
CC       coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-
CC       tetrahydromethanopterin. This is an energy-conserving, sodium-ion
CC       translocating step. {ECO:0000255|HAMAP-Rule:MF_01094}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme M + 2
CC         Na(+)(in) = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M + 2
CC         Na(+)(out); Xref=Rhea:RHEA:53492, ChEBI:CHEBI:29101,
CC         ChEBI:CHEBI:58103, ChEBI:CHEBI:58116, ChEBI:CHEBI:58286,
CC         ChEBI:CHEBI:58319; EC=2.1.1.86; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_01094};
CC   -!- PATHWAY: One-carbon metabolism; methanogenesis from CO(2); methyl-
CC       coenzyme M from 5,10-methylene-5,6,7,8-tetrahydromethanopterin: step
CC       2/2. {ECO:0000255|HAMAP-Rule:MF_01094}.
CC   -!- SUBUNIT: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD,
CC       MtrE, MtrF, MtrG and MtrH. {ECO:0000255|HAMAP-Rule:MF_01094}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01094};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01094}.
CC   -!- SIMILARITY: Belongs to the MtrB family. {ECO:0000255|HAMAP-
CC       Rule:MF_01094}.
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DR   EMBL; CP000745; ABR65877.1; -; Genomic_DNA.
DR   RefSeq; WP_011977195.1; NC_009637.1.
DR   AlphaFoldDB; A6VHF1; -.
DR   STRING; 426368.MmarC7_0810; -.
DR   EnsemblBacteria; ABR65877; ABR65877; MmarC7_0810.
DR   GeneID; 5328205; -.
DR   KEGG; mmz:MmarC7_0810; -.
DR   eggNOG; arCOG04867; Archaea.
DR   HOGENOM; CLU_171544_0_0_2; -.
DR   OMA; TNMVYGF; -.
DR   OrthoDB; 114178at2157; -.
DR   UniPathway; UPA00640; UER00698.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030269; F:tetrahydromethanopterin S-methyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019386; P:methanogenesis, from carbon dioxide; IEA:UniProtKB-UniPathway.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01094; MtrB; 1.
DR   InterPro; IPR008690; MtrB_MeTrfase.
DR   Pfam; PF05440; MtrB; 1.
DR   PIRSF; PIRSF005518; MtrB; 1.
DR   TIGRFAMs; TIGR04166; methano_MtrB; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Methanogenesis; Methyltransferase;
KW   One-carbon metabolism; Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..108
FT                   /note="Tetrahydromethanopterin S-methyltransferase subunit
FT                   B"
FT                   /id="PRO_1000064936"
FT   TRANSMEM        79..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01094"
SQ   SEQUENCE   108 AA;  12070 MW;  ACFB7428A3B1B31E CRC64;
     MDIVKVCPEL HIVMDVDSGL IAEMRKDILV VDLHPVEDEI NKLAQYAKAL ENSLDPRNSP
     MKAYNGREGT YKLAGMFQGM FFGFWVTMAI LVLVTILAVK MNLSLIGL