ID   MTRB_METMP              Reviewed;         108 AA.
AC   Q6LWZ1;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Tetrahydromethanopterin S-methyltransferase subunit B {ECO:0000255|HAMAP-Rule:MF_01094};
DE            EC=2.1.1.86 {ECO:0000255|HAMAP-Rule:MF_01094};
DE   AltName: Full=N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit B {ECO:0000255|HAMAP-Rule:MF_01094};
GN   Name=mtrB {ECO:0000255|HAMAP-Rule:MF_01094}; OrderedLocusNames=MMP1563;
OS   Methanococcus maripaludis (strain S2 / LL).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanococcaceae; Methanococcus.
OX   NCBI_TaxID=267377;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S2 / LL;
RX   PubMed=15466049; DOI=10.1128/jb.186.20.6956-6969.2004;
RA   Hendrickson E.L., Kaul R., Zhou Y., Bovee D., Chapman P., Chung J.,
RA   Conway de Macario E., Dodsworth J.A., Gillett W., Graham D.E., Hackett M.,
RA   Haydock A.K., Kang A., Land M.L., Levy R., Lie T.J., Major T.A.,
RA   Moore B.C., Porat I., Palmeiri A., Rouse G., Saenphimmachak C., Soell D.,
RA   Van Dien S., Wang T., Whitman W.B., Xia Q., Zhang Y., Larimer F.W.,
RA   Olson M.V., Leigh J.A.;
RT   "Complete genome sequence of the genetically tractable hydrogenotrophic
RT   methanogen Methanococcus maripaludis.";
RL   J. Bacteriol. 186:6956-6969(2004).
CC   -!- FUNCTION: Part of a complex that catalyzes the formation of methyl-
CC       coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-
CC       tetrahydromethanopterin. This is an energy-conserving, sodium-ion
CC       translocating step. {ECO:0000255|HAMAP-Rule:MF_01094}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme M + 2
CC         Na(+)(in) = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M + 2
CC         Na(+)(out); Xref=Rhea:RHEA:53492, ChEBI:CHEBI:29101,
CC         ChEBI:CHEBI:58103, ChEBI:CHEBI:58116, ChEBI:CHEBI:58286,
CC         ChEBI:CHEBI:58319; EC=2.1.1.86; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_01094};
CC   -!- PATHWAY: One-carbon metabolism; methanogenesis from CO(2); methyl-
CC       coenzyme M from 5,10-methylene-5,6,7,8-tetrahydromethanopterin: step
CC       2/2. {ECO:0000255|HAMAP-Rule:MF_01094}.
CC   -!- SUBUNIT: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD,
CC       MtrE, MtrF, MtrG and MtrH. {ECO:0000255|HAMAP-Rule:MF_01094}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01094};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01094}.
CC   -!- SIMILARITY: Belongs to the MtrB family. {ECO:0000255|HAMAP-
CC       Rule:MF_01094}.
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DR   EMBL; BX950229; CAF31119.1; -; Genomic_DNA.
DR   RefSeq; WP_011171507.1; NC_005791.1.
DR   AlphaFoldDB; Q6LWZ1; -.
DR   STRING; 267377.MMP1563; -.
DR   EnsemblBacteria; CAF31119; CAF31119; MMP1563.
DR   GeneID; 41280204; -.
DR   KEGG; mmp:MMP1563; -.
DR   PATRIC; fig|267377.15.peg.1601; -.
DR   eggNOG; arCOG04867; Archaea.
DR   HOGENOM; CLU_171544_0_0_2; -.
DR   OMA; TNMVYGF; -.
DR   OrthoDB; 114178at2157; -.
DR   BioCyc; MMAR267377:MMP_RS08045-MON; -.
DR   UniPathway; UPA00640; UER00698.
DR   Proteomes; UP000000590; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030269; F:tetrahydromethanopterin S-methyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019386; P:methanogenesis, from carbon dioxide; IEA:UniProtKB-UniPathway.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01094; MtrB; 1.
DR   InterPro; IPR008690; MtrB_MeTrfase.
DR   Pfam; PF05440; MtrB; 1.
DR   PIRSF; PIRSF005518; MtrB; 1.
DR   TIGRFAMs; TIGR04166; methano_MtrB; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Methanogenesis; Methyltransferase;
KW   One-carbon metabolism; Reference proteome; Transferase; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..108
FT                   /note="Tetrahydromethanopterin S-methyltransferase subunit
FT                   B"
FT                   /id="PRO_0000147517"
FT   TRANSMEM        77..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01094"
SQ   SEQUENCE   108 AA;  12027 MW;  ACFE32484A12701E CRC64;
     MDIVKVCPEL HIVMDVDSGL IAEMRKDILV VDLHPVEDEI NKLAQYAKAL ENSLDPRNTP
     MKAYAGREGT YKLAGMFQGM FFGFWVTMAV LVLVTILAVK MNLSLIGL