ID   MTRB_METVS              Reviewed;         108 AA.
AC   A6UQK9;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Tetrahydromethanopterin S-methyltransferase subunit B {ECO:0000255|HAMAP-Rule:MF_01094};
DE            EC=2.1.1.86 {ECO:0000255|HAMAP-Rule:MF_01094};
DE   AltName: Full=N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit B {ECO:0000255|HAMAP-Rule:MF_01094};
GN   Name=mtrB {ECO:0000255|HAMAP-Rule:MF_01094}; OrderedLocusNames=Mevan_0876;
OS   Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148
OS   / SB).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanococcaceae; Methanococcus.
OX   NCBI_TaxID=406327;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Anderson I.,
RA   Sieprawska-Lupa M., Whitman W.B., Richardson P.;
RT   "Complete sequence of Methanococcus vannielii SB.";
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of a complex that catalyzes the formation of methyl-
CC       coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-
CC       tetrahydromethanopterin. This is an energy-conserving, sodium-ion
CC       translocating step. {ECO:0000255|HAMAP-Rule:MF_01094}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme M + 2
CC         Na(+)(in) = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M + 2
CC         Na(+)(out); Xref=Rhea:RHEA:53492, ChEBI:CHEBI:29101,
CC         ChEBI:CHEBI:58103, ChEBI:CHEBI:58116, ChEBI:CHEBI:58286,
CC         ChEBI:CHEBI:58319; EC=2.1.1.86; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_01094};
CC   -!- PATHWAY: One-carbon metabolism; methanogenesis from CO(2); methyl-
CC       coenzyme M from 5,10-methylene-5,6,7,8-tetrahydromethanopterin: step
CC       2/2. {ECO:0000255|HAMAP-Rule:MF_01094}.
CC   -!- SUBUNIT: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD,
CC       MtrE, MtrF, MtrG and MtrH. {ECO:0000255|HAMAP-Rule:MF_01094}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01094};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01094}.
CC   -!- SIMILARITY: Belongs to the MtrB family. {ECO:0000255|HAMAP-
CC       Rule:MF_01094}.
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DR   EMBL; CP000742; ABR54781.1; -; Genomic_DNA.
DR   RefSeq; WP_011972682.1; NC_009634.1.
DR   AlphaFoldDB; A6UQK9; -.
DR   STRING; 406327.Mevan_0876; -.
DR   EnsemblBacteria; ABR54781; ABR54781; Mevan_0876.
DR   GeneID; 5326196; -.
DR   KEGG; mvn:Mevan_0876; -.
DR   eggNOG; arCOG04867; Archaea.
DR   HOGENOM; CLU_171544_0_0_2; -.
DR   OMA; TNMVYGF; -.
DR   OrthoDB; 114178at2157; -.
DR   UniPathway; UPA00640; UER00698.
DR   Proteomes; UP000001107; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030269; F:tetrahydromethanopterin S-methyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019386; P:methanogenesis, from carbon dioxide; IEA:UniProtKB-UniPathway.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01094; MtrB; 1.
DR   InterPro; IPR008690; MtrB_MeTrfase.
DR   Pfam; PF05440; MtrB; 1.
DR   PIRSF; PIRSF005518; MtrB; 1.
DR   TIGRFAMs; TIGR04166; methano_MtrB; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Methanogenesis; Methyltransferase;
KW   One-carbon metabolism; Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..108
FT                   /note="Tetrahydromethanopterin S-methyltransferase subunit
FT                   B"
FT                   /id="PRO_1000064937"
FT   TRANSMEM        79..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01094"
SQ   SEQUENCE   108 AA;  12132 MW;  E555AC5BD90E87A1 CRC64;
     MEIVKVCPEI HVVMDIDSGL IAEMRKDILV VDLHPVEEQI NKLAYFAKAL ENSLDPRNAP
     MKSYKGRDGT YKTGGLFQGM FFGFWVTMSI LVLVTILTIK MNLSLIGL