ID   MTRG_METMP              Reviewed;          74 AA.
AC   Q6LWY8;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Tetrahydromethanopterin S-methyltransferase subunit G {ECO:0000255|HAMAP-Rule:MF_01500};
DE            EC=2.1.1.86 {ECO:0000255|HAMAP-Rule:MF_01500};
DE   AltName: Full=N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit G {ECO:0000255|HAMAP-Rule:MF_01500};
GN   Name=mtrG {ECO:0000255|HAMAP-Rule:MF_01500}; OrderedLocusNames=MMP1566;
OS   Methanococcus maripaludis (strain S2 / LL).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanococcaceae; Methanococcus.
OX   NCBI_TaxID=267377;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S2 / LL;
RX   PubMed=15466049; DOI=10.1128/jb.186.20.6956-6969.2004;
RA   Hendrickson E.L., Kaul R., Zhou Y., Bovee D., Chapman P., Chung J.,
RA   Conway de Macario E., Dodsworth J.A., Gillett W., Graham D.E., Hackett M.,
RA   Haydock A.K., Kang A., Land M.L., Levy R., Lie T.J., Major T.A.,
RA   Moore B.C., Porat I., Palmeiri A., Rouse G., Saenphimmachak C., Soell D.,
RA   Van Dien S., Wang T., Whitman W.B., Xia Q., Zhang Y., Larimer F.W.,
RA   Olson M.V., Leigh J.A.;
RT   "Complete genome sequence of the genetically tractable hydrogenotrophic
RT   methanogen Methanococcus maripaludis.";
RL   J. Bacteriol. 186:6956-6969(2004).
CC   -!- FUNCTION: Part of a complex that catalyzes the formation of methyl-
CC       coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-
CC       tetrahydromethanopterin. This is an energy-conserving, sodium-ion
CC       translocating step. {ECO:0000255|HAMAP-Rule:MF_01500}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme M + 2
CC         Na(+)(in) = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M + 2
CC         Na(+)(out); Xref=Rhea:RHEA:53492, ChEBI:CHEBI:29101,
CC         ChEBI:CHEBI:58103, ChEBI:CHEBI:58116, ChEBI:CHEBI:58286,
CC         ChEBI:CHEBI:58319; EC=2.1.1.86; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_01500};
CC   -!- PATHWAY: One-carbon metabolism; methanogenesis from CO(2); methyl-
CC       coenzyme M from 5,10-methylene-5,6,7,8-tetrahydromethanopterin: step
CC       2/2. {ECO:0000255|HAMAP-Rule:MF_01500}.
CC   -!- SUBUNIT: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD,
CC       MtrE, MtrF, MtrG and MtrH. {ECO:0000255|HAMAP-Rule:MF_01500}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01500};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01500}.
CC   -!- SIMILARITY: Belongs to the MtrG family. {ECO:0000255|HAMAP-
CC       Rule:MF_01500}.
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DR   EMBL; BX950229; CAF31122.1; -; Genomic_DNA.
DR   RefSeq; WP_011171510.1; NC_005791.1.
DR   AlphaFoldDB; Q6LWY8; -.
DR   SMR; Q6LWY8; -.
DR   STRING; 267377.MMP1566; -.
DR   EnsemblBacteria; CAF31122; CAF31122; MMP1566.
DR   GeneID; 5737845; -.
DR   KEGG; mmp:MMP1566; -.
DR   PATRIC; fig|267377.15.peg.1604; -.
DR   eggNOG; arCOG03380; Archaea.
DR   HOGENOM; CLU_191926_0_0_2; -.
DR   OMA; PQVIMDP; -.
DR   OrthoDB; 130315at2157; -.
DR   BioCyc; MMAR267377:MMP_RS08060-MON; -.
DR   UniPathway; UPA00640; UER00698.
DR   Proteomes; UP000000590; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030269; F:tetrahydromethanopterin S-methyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019386; P:methanogenesis, from carbon dioxide; IEA:UniProtKB-UniPathway.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01500; MtrG; 1.
DR   InterPro; IPR005866; THM_MeTrfase_su_G.
DR   Pfam; PF04210; MtrG; 1.
DR   PIRSF; PIRSF006500; MtrG; 1.
DR   TIGRFAMs; TIGR01149; mtrG; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Methanogenesis; Methyltransferase;
KW   One-carbon metabolism; Reference proteome; Transferase; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..74
FT                   /note="Tetrahydromethanopterin S-methyltransferase subunit
FT                   G"
FT                   /id="PRO_0000147558"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01500"
SQ   SEQUENCE   74 AA;  8198 MW;  A11F07692A7906B0 CRC64;
     MSEIPTVVTP TKDYKRLQAK LDEIENTVEN TNAEIIQRTG KKAGRDVGIA YGLAIGFIFV
     YVLGTVLPLF DLIK