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MTS1A_DANRE
ID   MTS1A_DANRE             Reviewed;         440 AA.
AC   A0JMQ7;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Microtubule-associated tumor suppressor 1 homolog A;
DE   AltName: Full=Mitochondrial tumor suppressor 1 homolog A;
GN   Name=mtus1a; Synonyms=mtus1; ORFNames=zgc:154168;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May inhibit cell proliferation. {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}. Golgi apparatus
CC       {ECO:0000250}. Cell membrane {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MTUS1 family. {ECO:0000305}.
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DR   EMBL; BC125970; AAI25971.1; -; mRNA.
DR   RefSeq; NP_001071076.2; NM_001077608.2.
DR   AlphaFoldDB; A0JMQ7; -.
DR   SMR; A0JMQ7; -.
DR   STRING; 7955.ENSDARP00000108041; -.
DR   PaxDb; A0JMQ7; -.
DR   PRIDE; A0JMQ7; -.
DR   GeneID; 563853; -.
DR   KEGG; dre:563853; -.
DR   CTD; 563853; -.
DR   ZFIN; ZDB-GENE-061103-409; mtus1a.
DR   eggNOG; ENOG502QPVG; Eukaryota.
DR   InParanoid; A0JMQ7; -.
DR   OrthoDB; 70474at2759; -.
DR   PhylomeDB; A0JMQ7; -.
DR   PRO; PR:A0JMQ7; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   InterPro; IPR029786; MTUS1.
DR   PANTHER; PTHR24200:SF7; PTHR24200:SF7; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell membrane; Coiled coil; Golgi apparatus; Membrane;
KW   Mitochondrion; Nucleus; Reference proteome.
FT   CHAIN           1..440
FT                   /note="Microtubule-associated tumor suppressor 1 homolog A"
FT                   /id="PRO_0000305201"
FT   REGION          44..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          407..440
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          69..401
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        411..440
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   440 AA;  51209 MW;  7638E32BDB21B47A CRC64;
     MFFISKLSLS NIHVRLTAKG LLRNLQLLSG CKLAVGFLAV DKNKSRTNSK NPQPPTNGQP
     DLVPPESKSR NVEYYKAQCE KKNQTIRQLE NTLLSNNRRF EAVAVVIKHL YAEHDEVMKQ
     RRDLSQELVT LREELVSSGH SCERLEQEKE DLRSAFDGVL QKVQEQHRLD LADLEERLKT
     FYSTEWEKVH QAYQEEADKC KAQMEQQLEE IRSKHEALKK ELESSHIEEV DGLKQQFEES
     FKGFKQSHEK EMQNLNETLK ESEETLSNQI QDLMTENDSL KEKLNAEVKR RMELAEKTQD
     SHTLYLEQEL ESLKVVLDIK NKQIHEQDKK LMQIDKLMER NVKLDECLKK LQQENEDLKA
     RMDRHAALSR QLSTEQAVLQ ESLQKESKVN KRLSMENEEL LWKLHNGDLN SPRKISPSPS
     LNLQSPRTSG MFSSPPVSPR
 
 
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