ID   MTSA_LACLA              Reviewed;         313 AA.
AC   Q9CFZ5;
DT   18-OCT-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Metal ABC transporter substrate-binding lipoprotein;
DE   Flags: Precursor;
GN   Name=mtsA; OrderedLocusNames=LL1316; ORFNames=L148957;
OS   Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=272623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IL1403;
RX   PubMed=11337471; DOI=10.1101/gr.gr-1697r;
RA   Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J.,
RA   Ehrlich S.D., Sorokin A.;
RT   "The complete genome sequence of the lactic acid bacterium Lactococcus
RT   lactis ssp. lactis IL1403.";
RL   Genome Res. 11:731-753(2001).
CC   -!- FUNCTION: Part of an ATP-driven transport system for a metal; probably
CC       for manganese.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 9 family.
CC       Lipoprotein receptor antigen (Lrai) subfamily. {ECO:0000305}.
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DR   EMBL; AE005176; AAK05414.1; -; Genomic_DNA.
DR   PIR; D86789; D86789.
DR   RefSeq; NP_267472.1; NC_002662.1.
DR   AlphaFoldDB; Q9CFZ5; -.
DR   SMR; Q9CFZ5; -.
DR   STRING; 272623.L148957; -.
DR   PaxDb; Q9CFZ5; -.
DR   EnsemblBacteria; AAK05414; AAK05414; L148957.
DR   KEGG; lla:L148957; -.
DR   PATRIC; fig|272623.7.peg.1420; -.
DR   eggNOG; COG0803; Bacteria.
DR   HOGENOM; CLU_016838_1_1_9; -.
DR   OMA; HHVFGYL; -.
DR   Proteomes; UP000002196; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0030001; P:metal ion transport; IEA:InterPro.
DR   InterPro; IPR006129; AdhesinB.
DR   InterPro; IPR006128; Lipoprotein_4.
DR   InterPro; IPR006127; ZnuA-like.
DR   Pfam; PF01297; ZnuA; 1.
DR   PRINTS; PR00691; ADHESINB.
DR   PRINTS; PR00690; ADHESNFAMILY.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Manganese; Membrane; Metal-binding; Palmitate;
KW   Reference proteome; Signal; Transport; Zinc.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           24..313
FT                   /note="Metal ABC transporter substrate-binding lipoprotein"
FT                   /id="PRO_0000031883"
FT   BINDING         71
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250"
FT   BINDING         143
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250"
FT   BINDING         209
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250"
FT   BINDING         284
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250"
FT   LIPID           24
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           24
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   313 AA;  35500 MW;  9B146BFB15B3BD30 CRC64;
     MIEKYKNILI TFIALAAIVF LVGCSNKKTD QVTDKKINVV VTNSILADIT KNIADDKINL
     HSIVPVGKDP HEYEPLPVDV QKTSKADLIF YNGLNLETGG NAWFTKLVNN ANKKENIDYF
     PVSTGVEVIY LEGKNTEGKE DPHAWLNLEN GIIYAKNIEQ QLSKKDPVNK DFYKHNLDKY
     VKKLSDLDQQ AKSKFSLIPE NEKMIVTSEG CFKYFSKAYN IPSAYIWEIN TEEEGTPDQI
     KNLVRKLRAT ELKSLFVESS VDNRPMKTVS KDTGIPIYST IFTDSVAKKG ENGDSYYSMM
     KWNLDQIYKG LAK