ID   MTXA_METAC              Reviewed;         197 AA.
AC   Q8TPU9;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Putative methyltransferase Mtx subunit A;
DE            EC=2.1.1.-;
GN   Name=mtxA; OrderedLocusNames=MA_1805;
OS   Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 /
OS   C2A).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=188937;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A;
RX   PubMed=11932238; DOI=10.1101/gr.223902;
RA   Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W.,
RA   Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J.,
RA   Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.,
RA   McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D.,
RA   Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R.,
RA   Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J.,
RA   Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A.,
RA   White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H.,
RA   Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V.,
RA   Zinder S.H., Lander E., Metcalf W.W., Birren B.;
RT   "The genome of Methanosarcina acetivorans reveals extensive metabolic and
RT   physiological diversity.";
RL   Genome Res. 12:532-542(2002).
CC   -!- SUBUNIT: May be part of a complex composed of 3 subunits; MtxA, MtxH
CC       and MtxX. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MtrA family. {ECO:0000305}.
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DR   EMBL; AE010299; AAM05211.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8TPU9; -.
DR   SMR; Q8TPU9; -.
DR   STRING; 188937.MA_1805; -.
DR   EnsemblBacteria; AAM05211; AAM05211; MA_1805.
DR   KEGG; mac:MA_1805; -.
DR   HOGENOM; CLU_100863_0_0_2; -.
DR   OMA; AIWGSSK; -.
DR   PhylomeDB; Q8TPU9; -.
DR   Proteomes; UP000002487; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   InterPro; IPR030688; MeTrfase_MtrA/MtxA.
DR   Pfam; PF04208; MtrA; 1.
DR   PIRSF; PIRSF009452; MtrA_MtxA; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..197
FT                   /note="Putative methyltransferase Mtx subunit A"
FT                   /id="PRO_0000147509"
SQ   SEQUENCE   197 AA;  21478 MW;  8DD917B083C08A92 CRC64;
     MKTIAENWPP VRGDYVTGKP DSRIAVVTLA SHLEAFPNAA IWGSSKTENL GVEKIIVNVI
     SNSNIRYVLV CGTESRGHLA GHSLLAIHAN GIDEKGRIVG SQGAIPFIEN ISREAVDRFQ
     RQVTLLDRIG LNDPEEIRKI VEDYRDKGEV YPEEPVVVCA PKKRQASFAV PSSGDVIISE
     ELVMDSMAGI ICLAESL