ID   MTXA_METBF              Reviewed;         197 AA.
AC   O32854; Q46AT8;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Putative methyltransferase Mtx subunit A;
DE            EC=2.1.1.-;
GN   Name=mtxA; OrderedLocusNames=Mbar_A2073;
OS   Methanosarcina barkeri (strain Fusaro / DSM 804).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=269797;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9461302; DOI=10.1111/j.1432-1033.1997.00783.x;
RA   Harms U., Thauer R.K.;
RT   "Identification of the active site histidine in the corrinoid protein MtrA
RT   of the energy-conserving methyltransferase complex from Methanobacterium
RT   thermoautotrophicum.";
RL   Eur. J. Biochem. 250:783-788(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Fusaro / DSM 804;
RX   PubMed=16980466; DOI=10.1128/jb.00810-06;
RA   Maeder D.L., Anderson I., Brettin T.S., Bruce D.C., Gilna P., Han C.S.,
RA   Lapidus A., Metcalf W.W., Saunders E., Tapia R., Sowers K.R.;
RT   "The Methanosarcina barkeri genome: comparative analysis with
RT   Methanosarcina acetivorans and Methanosarcina mazei reveals extensive
RT   rearrangement within methanosarcinal genomes.";
RL   J. Bacteriol. 188:7922-7931(2006).
CC   -!- SUBUNIT: May be part of a complex composed of 3 subunits; MtxA, MtxH
CC       and MtxX.
CC   -!- SIMILARITY: Belongs to the MtrA family. {ECO:0000305}.
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DR   EMBL; Y14612; CAA74963.1; -; Genomic_DNA.
DR   EMBL; CP000099; AAZ71004.1; -; Genomic_DNA.
DR   AlphaFoldDB; O32854; -.
DR   SMR; O32854; -.
DR   STRING; 269797.Mbar_A2073; -.
DR   EnsemblBacteria; AAZ71004; AAZ71004; Mbar_A2073.
DR   KEGG; mba:Mbar_A2073; -.
DR   eggNOG; arCOG03220; Archaea.
DR   HOGENOM; CLU_100863_0_0_2; -.
DR   OMA; AIWGSSK; -.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   InterPro; IPR030688; MeTrfase_MtrA/MtxA.
DR   Pfam; PF04208; MtrA; 1.
DR   PIRSF; PIRSF009452; MtrA_MtxA; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Transferase.
FT   CHAIN           1..197
FT                   /note="Putative methyltransferase Mtx subunit A"
FT                   /id="PRO_0000147510"
SQ   SEQUENCE   197 AA;  21646 MW;  026DC4CCA341D962 CRC64;
     MKKIAEAWPI VKGDYTVGNP ESRIAVVTLA SQINSLPEAA LWGSSKTENL GVEKIIINTI
     SNSNIRYILI CGKESRGHLA GHSLLAIHAN GIDEKGRIVG SEGAIPFIEN ISREAVKRFQ
     QQVVLLDRIG LTNLEEIMKI VREYKDQGEV YPEEPLVAIS QKKRQSTFTI PHSGDIIVSE
     EFVMDSAAGV VCTTNDF